Cargando…
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes
The mechanisms regulating the disassembly of branched actin networks formed by the Arp2/3 complex still remain to be fully elucidated. In addition, the impact of Arp3 isoforms on the properties of Arp2/3 are also unexplored. We now demonstrate that Arp3 and Arp3B isocomplexes promote actin assembly...
Autores principales: | Galloni, Chiara, Carra, Davide, Abella, Jasmine V.G., Kjær, Svend, Singaravelu, Pavithra, Barry, David J., Kogata, Naoko, Guérin, Christophe, Blanchoin, Laurent, Way, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193582/ https://www.ncbi.nlm.nih.gov/pubmed/34106209 http://dx.doi.org/10.1083/jcb.202102043 |
Ejemplares similares
-
MICAL2 fine-tunes Arp2/3 for actin branching
por: Olson, Michael F., et al.
Publicado: (2021) -
Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms
por: von Loeffelholz, Ottilie, et al.
Publicado: (2020) -
Regulation of branched versus linear Arp2/3‐generated actin filaments
por: Cao, Luyan, et al.
Publicado: (2023) -
WAVE binds Ena/VASP for enhanced Arp2/3 complex–based actin assembly
por: Havrylenko, Svitlana, et al.
Publicado: (2015) -
Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly
por: Ingerman, Elena, et al.
Publicado: (2013)