Mikrobiom als natürlicher Schutzfaktor: Perspektiven aus der Grundlagenforschung

BACKGROUND: A new generation of technologies is uncovering a large number of microorganisms that are closely associated with the skin. Any disturbance of the interaction between skin cells and colonizing microbes has deleterious consequences. The impoverishment of the diversity of microbiome has been progressing for decades as part of a modern, globalized lifestyle. In maintaining good health, the microbes living in and on the skin and other organs must also be taken into account in addition to genetic aspects. All epithelia, including the skin, are colonized with a large number of microbes. OBJECTIVE: The function of the microbiome in the skin and other organs is described. MATERIALS AND METHODS: Basic research papers are discussed. RESULTS: The microbiome of the skin is very important for maintaining healthy skin. CONCLUSIONS: We need to understand our body as a multiorganismic metaorganism in order to be able to react intelligently to the challenges of a continually changing environment.