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COVID-19 vaccine acceptance among high-risk populations in Uganda
BACKGROUND: Immunization is an important strategy for controlling the COVID-19 pandemic. COVID-19 vaccination was recently launched in Uganda, with prioritization to healthcare workers and high-risk individuals. In this study, we aimed to determine the acceptability of COVID-19 vaccine among persons...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193654/ https://www.ncbi.nlm.nih.gov/pubmed/34178323 http://dx.doi.org/10.1177/20499361211024376 |
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author | Bongomin, Felix Olum, Ronald Andia-Biraro, Irene Nakwagala, Frederick Nelson Hassan, Khalid Hudow Nassozi, Dianah Rhoda Kaddumukasa, Mark Byakika-Kibwika, Pauline Kiguli, Sarah Kirenga, Bruce J. |
author_facet | Bongomin, Felix Olum, Ronald Andia-Biraro, Irene Nakwagala, Frederick Nelson Hassan, Khalid Hudow Nassozi, Dianah Rhoda Kaddumukasa, Mark Byakika-Kibwika, Pauline Kiguli, Sarah Kirenga, Bruce J. |
author_sort | Bongomin, Felix |
collection | PubMed |
description | BACKGROUND: Immunization is an important strategy for controlling the COVID-19 pandemic. COVID-19 vaccination was recently launched in Uganda, with prioritization to healthcare workers and high-risk individuals. In this study, we aimed to determine the acceptability of COVID-19 vaccine among persons at high risk of COVID-19 morbidity and mortality in Uganda. METHODS: Between 29 March and 14 April 2021, we conducted a cross-sectional survey consecutively recruiting persons at high risk of severe COVID-19 (diabetes mellitus, HIV and cardiovascular disease) attending Kiruddu National Referral Hospital outpatient clinics. A trained research nurse administered a semi-structured questionnaire assessing demographics, COVID-19 vaccine related attitudes and acceptability. Descriptive statistics, bivariate and multivariable analyses were performed using STATA 16. RESULTS: A total of 317 participants with a mean age 51.5 ± 14.1 years were recruited. Of this, 184 (60.5%) were female. Overall, 216 (70.1%) participants were willing to accept the COVID-19 vaccine. The odds of willingness to accept COVID-19 vaccination were four times greater if a participant was male compared with if a participant was female [adjusted odds ratio (AOR): 4.1, 95% confidence interval (CI): 1.8–9.4, p = 0.00]. Participants who agreed (AOR: 0.04, 95% CI: 0.01–0.38, p = 0.003) or strongly agreed (AOR: 0.04, 95% CI: 0.01–0.59, p = 0.005) that they have some immunity against COVID-19 were also significantly less likely to accept the vaccine. Participants who had a history of vaccination hesitancy for their children were also significantly less likely to accept the COVID-19 vaccine (AOR: 0.1, 95% CI: 0.01–0.58, p = 0.016). CONCLUSION: The willingness to receive a COVID-19 vaccine in this group of high-risk individuals was comparable to the global COVID-19 vaccine acceptance rate. Increased sensitization, myth busting and utilization of opinion leaders to encourage vaccine acceptability is recommended. |
format | Online Article Text |
id | pubmed-8193654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-81936542021-06-24 COVID-19 vaccine acceptance among high-risk populations in Uganda Bongomin, Felix Olum, Ronald Andia-Biraro, Irene Nakwagala, Frederick Nelson Hassan, Khalid Hudow Nassozi, Dianah Rhoda Kaddumukasa, Mark Byakika-Kibwika, Pauline Kiguli, Sarah Kirenga, Bruce J. Ther Adv Infect Dis Original Research BACKGROUND: Immunization is an important strategy for controlling the COVID-19 pandemic. COVID-19 vaccination was recently launched in Uganda, with prioritization to healthcare workers and high-risk individuals. In this study, we aimed to determine the acceptability of COVID-19 vaccine among persons at high risk of COVID-19 morbidity and mortality in Uganda. METHODS: Between 29 March and 14 April 2021, we conducted a cross-sectional survey consecutively recruiting persons at high risk of severe COVID-19 (diabetes mellitus, HIV and cardiovascular disease) attending Kiruddu National Referral Hospital outpatient clinics. A trained research nurse administered a semi-structured questionnaire assessing demographics, COVID-19 vaccine related attitudes and acceptability. Descriptive statistics, bivariate and multivariable analyses were performed using STATA 16. RESULTS: A total of 317 participants with a mean age 51.5 ± 14.1 years were recruited. Of this, 184 (60.5%) were female. Overall, 216 (70.1%) participants were willing to accept the COVID-19 vaccine. The odds of willingness to accept COVID-19 vaccination were four times greater if a participant was male compared with if a participant was female [adjusted odds ratio (AOR): 4.1, 95% confidence interval (CI): 1.8–9.4, p = 0.00]. Participants who agreed (AOR: 0.04, 95% CI: 0.01–0.38, p = 0.003) or strongly agreed (AOR: 0.04, 95% CI: 0.01–0.59, p = 0.005) that they have some immunity against COVID-19 were also significantly less likely to accept the vaccine. Participants who had a history of vaccination hesitancy for their children were also significantly less likely to accept the COVID-19 vaccine (AOR: 0.1, 95% CI: 0.01–0.58, p = 0.016). CONCLUSION: The willingness to receive a COVID-19 vaccine in this group of high-risk individuals was comparable to the global COVID-19 vaccine acceptance rate. Increased sensitization, myth busting and utilization of opinion leaders to encourage vaccine acceptability is recommended. SAGE Publications 2021-06-09 /pmc/articles/PMC8193654/ /pubmed/34178323 http://dx.doi.org/10.1177/20499361211024376 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Bongomin, Felix Olum, Ronald Andia-Biraro, Irene Nakwagala, Frederick Nelson Hassan, Khalid Hudow Nassozi, Dianah Rhoda Kaddumukasa, Mark Byakika-Kibwika, Pauline Kiguli, Sarah Kirenga, Bruce J. COVID-19 vaccine acceptance among high-risk populations in Uganda |
title | COVID-19 vaccine acceptance among high-risk populations in Uganda |
title_full | COVID-19 vaccine acceptance among high-risk populations in Uganda |
title_fullStr | COVID-19 vaccine acceptance among high-risk populations in Uganda |
title_full_unstemmed | COVID-19 vaccine acceptance among high-risk populations in Uganda |
title_short | COVID-19 vaccine acceptance among high-risk populations in Uganda |
title_sort | covid-19 vaccine acceptance among high-risk populations in uganda |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193654/ https://www.ncbi.nlm.nih.gov/pubmed/34178323 http://dx.doi.org/10.1177/20499361211024376 |
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