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Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter

Background and Purpose: Low-profile flow diverter stents (FDS) quite recently amended peripheral segments as targets for hemodynamic aneurysm treatment; however, reports on outcomes, especially later than 3 months, are scarce. This study therefore reports our experience with the novel silk vista bab...

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Autores principales: Schüngel, Marie-Sophie, Quäschling, Ulf, Weber, Erik, Struck, Manuel Florian, Maybaum, Jens, Bailis, Nikolaos, Arlt, Felix, Richter, Cindy, Hoffmann, Karl-Titus, Scherlach, Cordula, Schob, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193674/
https://www.ncbi.nlm.nih.gov/pubmed/34122317
http://dx.doi.org/10.3389/fneur.2021.671915
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author Schüngel, Marie-Sophie
Quäschling, Ulf
Weber, Erik
Struck, Manuel Florian
Maybaum, Jens
Bailis, Nikolaos
Arlt, Felix
Richter, Cindy
Hoffmann, Karl-Titus
Scherlach, Cordula
Schob, Stefan
author_facet Schüngel, Marie-Sophie
Quäschling, Ulf
Weber, Erik
Struck, Manuel Florian
Maybaum, Jens
Bailis, Nikolaos
Arlt, Felix
Richter, Cindy
Hoffmann, Karl-Titus
Scherlach, Cordula
Schob, Stefan
author_sort Schüngel, Marie-Sophie
collection PubMed
description Background and Purpose: Low-profile flow diverter stents (FDS) quite recently amended peripheral segments as targets for hemodynamic aneurysm treatment; however, reports on outcomes, especially later than 3 months, are scarce. This study therefore reports our experience with the novel silk vista baby (SVB) FDS and respective outcomes after 8 and 11 months with special respect to specific adverse events. Materials and Methods: Forty-four patients (mean age, 53 years) harboring 47 aneurysms treated with the SVB between June 2018 and December 2019 were included in our study. Clinical, procedural, and angiographic data were collected. Follow-ups were performed on average after 3, 8, and 11 months, respectively. Treatment effect was assessed using the O'Kelly Marotta (OKM) grading system. Results: Overall, angiographic follow-ups were available for 41 patients/45 aneurysms. Occlusion or significant reduction in aneurysmal perfusion (OKM: D1, B1–B3 and A2–A3) was observed in 98% of all aneurysms after 8 months. Only 2% of the treated aneurysms remained morphologically unaltered and without an apparent change in perfusion (OKM A1). Adverse events in the early post-interventional course occurred in seven patients; out of them, mRS-relevant morbidity at 90 days related to FDS treatment was observable in two patients. One death occurred in the context of severe SAH related to an acutely ruptured dissecting aneurysm of the vertebral artery. Conclusion: The SVB achieves sufficient occlusion rates of intracranial aneurysms originating from peripheral segments, which are comparable to prior established conventional FDS with acceptably low complication rates. However, alteration of a hemodynamic equilibrium in distal localizations requires special attention to prevent ischemic events.
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spelling pubmed-81936742021-06-12 Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter Schüngel, Marie-Sophie Quäschling, Ulf Weber, Erik Struck, Manuel Florian Maybaum, Jens Bailis, Nikolaos Arlt, Felix Richter, Cindy Hoffmann, Karl-Titus Scherlach, Cordula Schob, Stefan Front Neurol Neurology Background and Purpose: Low-profile flow diverter stents (FDS) quite recently amended peripheral segments as targets for hemodynamic aneurysm treatment; however, reports on outcomes, especially later than 3 months, are scarce. This study therefore reports our experience with the novel silk vista baby (SVB) FDS and respective outcomes after 8 and 11 months with special respect to specific adverse events. Materials and Methods: Forty-four patients (mean age, 53 years) harboring 47 aneurysms treated with the SVB between June 2018 and December 2019 were included in our study. Clinical, procedural, and angiographic data were collected. Follow-ups were performed on average after 3, 8, and 11 months, respectively. Treatment effect was assessed using the O'Kelly Marotta (OKM) grading system. Results: Overall, angiographic follow-ups were available for 41 patients/45 aneurysms. Occlusion or significant reduction in aneurysmal perfusion (OKM: D1, B1–B3 and A2–A3) was observed in 98% of all aneurysms after 8 months. Only 2% of the treated aneurysms remained morphologically unaltered and without an apparent change in perfusion (OKM A1). Adverse events in the early post-interventional course occurred in seven patients; out of them, mRS-relevant morbidity at 90 days related to FDS treatment was observable in two patients. One death occurred in the context of severe SAH related to an acutely ruptured dissecting aneurysm of the vertebral artery. Conclusion: The SVB achieves sufficient occlusion rates of intracranial aneurysms originating from peripheral segments, which are comparable to prior established conventional FDS with acceptably low complication rates. However, alteration of a hemodynamic equilibrium in distal localizations requires special attention to prevent ischemic events. Frontiers Media S.A. 2021-05-28 /pmc/articles/PMC8193674/ /pubmed/34122317 http://dx.doi.org/10.3389/fneur.2021.671915 Text en Copyright © 2021 Schüngel, Quäschling, Weber, Struck, Maybaum, Bailis, Arlt, Richter, Hoffmann, Scherlach and Schob. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Schüngel, Marie-Sophie
Quäschling, Ulf
Weber, Erik
Struck, Manuel Florian
Maybaum, Jens
Bailis, Nikolaos
Arlt, Felix
Richter, Cindy
Hoffmann, Karl-Titus
Scherlach, Cordula
Schob, Stefan
Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title_full Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title_fullStr Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title_full_unstemmed Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title_short Endovascular Treatment of Intracranial Aneurysms in Small Peripheral Vessel Segments—Efficacy and Intermediate Follow-Up Results of Flow Diversion With the Silk Vista Baby Low-Profile Flow Diverter
title_sort endovascular treatment of intracranial aneurysms in small peripheral vessel segments—efficacy and intermediate follow-up results of flow diversion with the silk vista baby low-profile flow diverter
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193674/
https://www.ncbi.nlm.nih.gov/pubmed/34122317
http://dx.doi.org/10.3389/fneur.2021.671915
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