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Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child

Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The...

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Autores principales: Nasr, Nathalie, Delamarre, Louis, Cheuret, Emmanuel, Chausseray, Gerald, Olivot, Jean Marc, Acar, Philippe, Bonneville, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193682/
https://www.ncbi.nlm.nih.gov/pubmed/34122315
http://dx.doi.org/10.3389/fneur.2021.670565
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author Nasr, Nathalie
Delamarre, Louis
Cheuret, Emmanuel
Chausseray, Gerald
Olivot, Jean Marc
Acar, Philippe
Bonneville, Fabrice
author_facet Nasr, Nathalie
Delamarre, Louis
Cheuret, Emmanuel
Chausseray, Gerald
Olivot, Jean Marc
Acar, Philippe
Bonneville, Fabrice
author_sort Nasr, Nathalie
collection PubMed
description Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The patient presented with right hemiplegia, central facial palsy, a normal level of consciousness, and speech difficulties. The PedNIHS score was 11. CT scan without contrast injection displayed spontaneous hyperdensity of the middle cerebral artery (MCA), with only limited early signs of ischemia (ASPECTS 8). CT angiography demonstrated occlusion of the proximal MCA with good collaterals. Thrombectomy was realized. Complete recanalization (TICI 3) was obtained under general anesthesia after two passes of a stent retriever. Time from symptoms onset to full recanalization was 9 h. The acute ischemic stroke was caused by embolic thrombus from a congenital heart disease. Clinical recovery was complete. Three months after the thrombectomy, the young patient was doing well without any neurological sequelae (PedNIHSS 0; modified Rankin Scale: 0). This case report is an example of a decision-making process to perform thrombectomy in a very young child, which included cardio-embolic etiology as a parameter that potentially might have participated to the successful outcome of the therapeutic procedure.
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spelling pubmed-81936822021-06-12 Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child Nasr, Nathalie Delamarre, Louis Cheuret, Emmanuel Chausseray, Gerald Olivot, Jean Marc Acar, Philippe Bonneville, Fabrice Front Neurol Neurology Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The patient presented with right hemiplegia, central facial palsy, a normal level of consciousness, and speech difficulties. The PedNIHS score was 11. CT scan without contrast injection displayed spontaneous hyperdensity of the middle cerebral artery (MCA), with only limited early signs of ischemia (ASPECTS 8). CT angiography demonstrated occlusion of the proximal MCA with good collaterals. Thrombectomy was realized. Complete recanalization (TICI 3) was obtained under general anesthesia after two passes of a stent retriever. Time from symptoms onset to full recanalization was 9 h. The acute ischemic stroke was caused by embolic thrombus from a congenital heart disease. Clinical recovery was complete. Three months after the thrombectomy, the young patient was doing well without any neurological sequelae (PedNIHSS 0; modified Rankin Scale: 0). This case report is an example of a decision-making process to perform thrombectomy in a very young child, which included cardio-embolic etiology as a parameter that potentially might have participated to the successful outcome of the therapeutic procedure. Frontiers Media S.A. 2021-05-28 /pmc/articles/PMC8193682/ /pubmed/34122315 http://dx.doi.org/10.3389/fneur.2021.670565 Text en Copyright © 2021 Nasr, Delamarre, Cheuret, Chausseray, Olivot, Acar and Bonneville. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Nasr, Nathalie
Delamarre, Louis
Cheuret, Emmanuel
Chausseray, Gerald
Olivot, Jean Marc
Acar, Philippe
Bonneville, Fabrice
Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title_full Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title_fullStr Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title_full_unstemmed Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title_short Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
title_sort case report: late successful thrombectomy for ischemic stroke in a 2-year-old child
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193682/
https://www.ncbi.nlm.nih.gov/pubmed/34122315
http://dx.doi.org/10.3389/fneur.2021.670565
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