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Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child
Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193682/ https://www.ncbi.nlm.nih.gov/pubmed/34122315 http://dx.doi.org/10.3389/fneur.2021.670565 |
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author | Nasr, Nathalie Delamarre, Louis Cheuret, Emmanuel Chausseray, Gerald Olivot, Jean Marc Acar, Philippe Bonneville, Fabrice |
author_facet | Nasr, Nathalie Delamarre, Louis Cheuret, Emmanuel Chausseray, Gerald Olivot, Jean Marc Acar, Philippe Bonneville, Fabrice |
author_sort | Nasr, Nathalie |
collection | PubMed |
description | Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The patient presented with right hemiplegia, central facial palsy, a normal level of consciousness, and speech difficulties. The PedNIHS score was 11. CT scan without contrast injection displayed spontaneous hyperdensity of the middle cerebral artery (MCA), with only limited early signs of ischemia (ASPECTS 8). CT angiography demonstrated occlusion of the proximal MCA with good collaterals. Thrombectomy was realized. Complete recanalization (TICI 3) was obtained under general anesthesia after two passes of a stent retriever. Time from symptoms onset to full recanalization was 9 h. The acute ischemic stroke was caused by embolic thrombus from a congenital heart disease. Clinical recovery was complete. Three months after the thrombectomy, the young patient was doing well without any neurological sequelae (PedNIHSS 0; modified Rankin Scale: 0). This case report is an example of a decision-making process to perform thrombectomy in a very young child, which included cardio-embolic etiology as a parameter that potentially might have participated to the successful outcome of the therapeutic procedure. |
format | Online Article Text |
id | pubmed-8193682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81936822021-06-12 Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child Nasr, Nathalie Delamarre, Louis Cheuret, Emmanuel Chausseray, Gerald Olivot, Jean Marc Acar, Philippe Bonneville, Fabrice Front Neurol Neurology Despite extensive evidence of benefit of thrombectomy in adult ischemic stroke due to large-vessel occlusion in the 6-h window, its role remains uncertain in very young children. We describe hereafter the case of a 2-year-old female child who had a successful thrombectomy 9 h after stroke onset. The patient presented with right hemiplegia, central facial palsy, a normal level of consciousness, and speech difficulties. The PedNIHS score was 11. CT scan without contrast injection displayed spontaneous hyperdensity of the middle cerebral artery (MCA), with only limited early signs of ischemia (ASPECTS 8). CT angiography demonstrated occlusion of the proximal MCA with good collaterals. Thrombectomy was realized. Complete recanalization (TICI 3) was obtained under general anesthesia after two passes of a stent retriever. Time from symptoms onset to full recanalization was 9 h. The acute ischemic stroke was caused by embolic thrombus from a congenital heart disease. Clinical recovery was complete. Three months after the thrombectomy, the young patient was doing well without any neurological sequelae (PedNIHSS 0; modified Rankin Scale: 0). This case report is an example of a decision-making process to perform thrombectomy in a very young child, which included cardio-embolic etiology as a parameter that potentially might have participated to the successful outcome of the therapeutic procedure. Frontiers Media S.A. 2021-05-28 /pmc/articles/PMC8193682/ /pubmed/34122315 http://dx.doi.org/10.3389/fneur.2021.670565 Text en Copyright © 2021 Nasr, Delamarre, Cheuret, Chausseray, Olivot, Acar and Bonneville. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Nasr, Nathalie Delamarre, Louis Cheuret, Emmanuel Chausseray, Gerald Olivot, Jean Marc Acar, Philippe Bonneville, Fabrice Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title | Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title_full | Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title_fullStr | Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title_full_unstemmed | Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title_short | Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child |
title_sort | case report: late successful thrombectomy for ischemic stroke in a 2-year-old child |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193682/ https://www.ncbi.nlm.nih.gov/pubmed/34122315 http://dx.doi.org/10.3389/fneur.2021.670565 |
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