Cargando…

Podocyte Sphingolipid Signaling in Nephrotic Syndrome

Podocytes play a vital role in the pathogenesis of nephrotic syndrome (NS), which is clinically characterized by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and peripheral edema. The pathogenesis of NS has evolved through several hypotheses ranging from immune dysregulation theory and increa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Guangbi, Kidd, Jason, Gehr, Todd W.B., Li, Pin-Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193717/ https://www.ncbi.nlm.nih.gov/pubmed/33861526 http://dx.doi.org/10.33594/000000356

Ejemplares similares

Abnormal podocyte TRPML1 channel activity and exosome release in mice with podocyte-specific Asah1 gene deletion
por: Li, Guangbi, et al.
Publicado: (2020)

Podocyte Lysosome Dysfunction in Chronic Glomerular Diseases
por: Li, Guangbi, et al.
Publicado: (2020)

Current concepts of the podocyte in nephrotic syndrome
por: Ding, Wen Y., et al.
Publicado: (2012)

Nutrition for Podocyte Repair in Nephrotic Syndrome?
por: Aquilani, Roberto, et al.
Publicado: (2023)

The Role of Glucocorticoid Receptors in Podocytes and Nephrotic Syndrome
por: Zhao, Xuan, et al.
Publicado: (2018)

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome
por: Veissi, Susan T., et al.
Publicado: (2023)

Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes
por: Li, Guangbi, et al.
Publicado: (2021)

Podocyte Pathology and Nephropathy – Sphingolipids in Glomerular Diseases
por: Merscher, Sandra, et al.
Publicado: (2014)

APOL1 polymorphism modulates sphingolipid profile of human podocytes
por: Valsecchi, Manuela, et al.
Publicado: (2020)

D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway
por: Hong, Jinni, et al.
Publicado: (2019)

Podocyte RhoGTPases: new therapeutic targets for nephrotic syndrome?
por: Saleem, Moin A., et al.
Publicado: (2019)

Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?
por: Zea, Arnold H., et al.
Publicado: (2016)

Expression profiling of cultured podocytes exposed to nephrotic plasma reveals intrinsic molecular signatures of nephrotic syndrome
por: Panigrahi, Stuti, et al.
Publicado: (2020)

Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Containing Pyrin Domain 3 Inflammasome Activation
por: Zhang, Qinghua, et al.
Publicado: (2019)

Lysosomal regulation of extracellular vesicle excretion during D-ribose-induced NLRP3 inflammasome activation in podocytes
por: Hong, Jinni, et al.
Publicado: (2019)

Podocyte secreted Angiopoietin-like 4 mediates proteinuria in glucocorticoid sensitive nephrotic syndrome
por: Clement, Lionel C., et al.
Publicado: (2010)

Comparison between outcomes of IgA nephropathy with nephrotic-range proteinuria and nephrotic syndrome: do podocytes play a role?
por: Chen, Yizhen, et al.
Publicado: (2022)

IL-17 aggravates renal injury by promoting podocyte injury in children with primary nephrotic syndrome
por: Zhai, Shubo, et al.
Publicado: (2020)

Activation of TRPC6 by AngⅡ Induces Podocyte Injury and Participates in Proteinuria of Nephrotic Syndrome
por: Feng, Ye, et al.
Publicado: (2022)

Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes
por: Xiong, Jing, et al.
Publicado: (2013)

Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton Stabilization
por: Bergwall, Lovisa, et al.
Publicado: (2018)

Engineering antioxidant ceria-zirconia nanomedicines for alleviating podocyte injury in rats with adriamycin-induced nephrotic syndrome
por: Liu, Lili, et al.
Publicado: (2023)

Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome
por: Ogawa-Akiyama, Ayu, et al.
Publicado: (2020)

Disarranged Sphingolipid Metabolism From Sphingosine-1-Phosphate Lyase Deficiency Leads to Congenital Nephrotic Syndrome
por: Taylor, Veronica A., et al.
Publicado: (2019)

tRNA-Derived Fragments in Podocytes with Adriamycin-Induced Injury Reveal the Potential Mechanism of Idiopathic Nephrotic Syndrome
por: Li, Shanwen, et al.
Publicado: (2020)

Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis
por: Lane, Brandon M., et al.
Publicado: (2022)

Decreased Podocyte Vesicle Transcytosis and Albuminuria in APC C-Terminal Deficiency Mice with Puromycin-Induced Nephrotic Syndrome
por: Hatakeyama, Saaya, et al.
Publicado: (2021)

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome
por: Yang, Xuejun, et al.
Publicado: (2018)

Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations
por: Benoit, Geneviève, et al.
Publicado: (2010)

The pleiotropic roles of sphingolipid signaling in autophagy
por: Li, Y, et al.
Publicado: (2014)

The pleiotropic roles of sphingolipid signaling in autophagy
por: Li, Y, et al.
Publicado: (2014)

Steroid-Responsive Nephrotic Syndrome and Bilateral Renal Artery Stenosis: A Possible Role for Angiotensin-Mediated Podocyte Injury
por: Bhardwaj, Rahul, et al.
Publicado: (2012)

The Effect of Interleukin-4 and Dexamethasone on RNA-Seq-Based Transcriptomic Profiling of Human Podocytes: A Potential Role in Minimal Change Nephrotic Syndrome
por: Lee, Jiwon M., et al.
Publicado: (2021)

The Equilibria of Sphingolipid-Cholesterol and Sphingolipid–Sphingolipid in Monolayers at the Air–Water Interface
por: Petelska, Aneta Dorota, et al.
Publicado: (2012)

Studies in the Nephrotic Syndrome
por: Lyon, D. M., et al.
Publicado: (1935)

The role of sphingolipid signalling in diabetes-associated pathologies (Review)
por: Ng, Mei Li, et al.
Publicado: (2017)

Complications of nephrotic syndrome
por: Park, Se Jin, et al.
Publicado: (2011)

Eczema craquelé associated with nephrotic syndrome
por: Yang, Catherine S., et al.
Publicado: (2016)

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene
por: Boini, Krishna M., et al.
Publicado: (2016)

Sphingolipid metabolism and signaling in cardiovascular diseases
por: Borodzicz-Jażdżyk, Sonia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6dgk6nq3otl1mu2uk0k23kqehb