Combination of AZD3463 and DZNep Prevents Bone Metastasis of Breast Cancer by Suppressing Akt Signaling

Osteolysis resulting from osteoclast overactivation is one of the severe complications of breast cancer metastasis to the bone. Previous studies reported that the anti-cancer agent DZNep induces cancer cell apoptosis by activating Akt signaling. However, the effect of DZNep on breast cancer bone met...

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Detalles Bibliográficos
Autores principales: He, Wenxin, Cao, Xiankun, Rong, Kewei, Chen, Xiaojun, Han, Shuai, Qin, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193724/
https://www.ncbi.nlm.nih.gov/pubmed/34122074
http://dx.doi.org/10.3389/fphar.2021.652071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193724/
https://www.ncbi.nlm.nih.gov/pubmed/34122074
http://dx.doi.org/10.3389/fphar.2021.652071

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