Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice

Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Appro...

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Autores principales: Zhang, Yang, Zhang, Tao, Yang, Wenbo, Chen, Hongze, Geng, Xinglong, Li, Guanqun, Chen, Hua, Wang, Yongwei, Li, Le, Sun, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193730/
https://www.ncbi.nlm.nih.gov/pubmed/34123787
http://dx.doi.org/10.3389/fonc.2021.630972
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author Zhang, Yang
Zhang, Tao
Yang, Wenbo
Chen, Hongze
Geng, Xinglong
Li, Guanqun
Chen, Hua
Wang, Yongwei
Li, Le
Sun, Bei
author_facet Zhang, Yang
Zhang, Tao
Yang, Wenbo
Chen, Hongze
Geng, Xinglong
Li, Guanqun
Chen, Hua
Wang, Yongwei
Li, Le
Sun, Bei
author_sort Zhang, Yang
collection PubMed
description Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Approximately 50% of PC cases are induced by an unhealthy diet, which can be avoided. Given this large attribution to diet, numerous studies have assessed the relationship between various dietary factors and PC. This article reviews three beneficial diets: a ketogenic diet (KD), a Mediterranean diet (MD), and a low-sugar diet. Their composition and impact mechanism are summarized and discussed. The associations between these three diets and PC were analyzed, and we aimed to provide more help and new insights for the prevention and treatment of PC.
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spelling pubmed-81937302021-06-12 Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice Zhang, Yang Zhang, Tao Yang, Wenbo Chen, Hongze Geng, Xinglong Li, Guanqun Chen, Hua Wang, Yongwei Li, Le Sun, Bei Front Oncol Oncology Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Approximately 50% of PC cases are induced by an unhealthy diet, which can be avoided. Given this large attribution to diet, numerous studies have assessed the relationship between various dietary factors and PC. This article reviews three beneficial diets: a ketogenic diet (KD), a Mediterranean diet (MD), and a low-sugar diet. Their composition and impact mechanism are summarized and discussed. The associations between these three diets and PC were analyzed, and we aimed to provide more help and new insights for the prevention and treatment of PC. Frontiers Media S.A. 2021-05-28 /pmc/articles/PMC8193730/ /pubmed/34123787 http://dx.doi.org/10.3389/fonc.2021.630972 Text en Copyright © 2021 Zhang, Zhang, Yang, Chen, Geng, Li, Chen, Wang, Li and Sun https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zhang, Yang
Zhang, Tao
Yang, Wenbo
Chen, Hongze
Geng, Xinglong
Li, Guanqun
Chen, Hua
Wang, Yongwei
Li, Le
Sun, Bei
Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title_full Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title_fullStr Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title_full_unstemmed Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title_short Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice
title_sort beneficial diets and pancreatic cancer: molecular mechanisms and clinical practice
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193730/
https://www.ncbi.nlm.nih.gov/pubmed/34123787
http://dx.doi.org/10.3389/fonc.2021.630972
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