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Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial

INTRODUCTION: Colonoscopy is considered the gold standard for colorectal cancer screening. Panoramic colonoscopy offers better visualization to decrease the adenoma miss rate. AIM: To assess the influence of 330° panoramic view colonoscopy on adenoma and polyp detection rate, cecal intubation time,...

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Autores principales: Bogacki, Paweł, Gach, Tomasz, Krzak, Jan, Szura, Miroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193743/
https://www.ncbi.nlm.nih.gov/pubmed/34136023
http://dx.doi.org/10.5114/wiitm.2021.103922
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author Bogacki, Paweł
Gach, Tomasz
Krzak, Jan
Szura, Miroslaw
author_facet Bogacki, Paweł
Gach, Tomasz
Krzak, Jan
Szura, Miroslaw
author_sort Bogacki, Paweł
collection PubMed
description INTRODUCTION: Colonoscopy is considered the gold standard for colorectal cancer screening. Panoramic colonoscopy offers better visualization to decrease the adenoma miss rate. AIM: To assess the influence of 330° panoramic view colonoscopy on adenoma and polyp detection rate, cecal intubation time, and examiner’s comfort. MATERIAL AND METHODS: The study enrolled 421 patients aged 18–80 years who were eligible for colonoscopy screening. Patients with prior abdominal surgery, inflammatory bowel disease or after colorectal resections were excluded from the study. Patients were randomized to either standard frontal view (SFV) (Olympus Evis Exera III 190 CF-HQ190L) or the panoramic view colonoscopy (PVC) (FUSE CDVL slim c38). The study was approved by the local bioethics committee and registered at ClinicalTrial.gov (NCT02929381). RESULTS: There were 214 patients examined with SFV and 207 with PVC. The mean age of patients was 64 ±12.26 years. The two groups were comparable. The median cecal intubation time was 234 s with SFV vs. 311 s with PVC (p < 0.001). There were no significant differences in CIR or withdrawal time. PVC made it possible to discover more diverticula in the ascending colon (p = 0.009). PDR with SFV was 34.6% and 40.1% with PVC (p = 0.242). A higher number of polyps was found in the transverse colon in the PVC group (p = 0.006). ADR and advanced ADR (aADR) in both groups were similar (26.4% vs. 27.1% and 14, 2% vs. 13.9%). CONCLUSIONS: Colonoscopy with wide-angle endoscopes lasts longer and allows for the detection of more polyps and diverticula without affecting ADR and aADR. Our study did not reveal the superiority of wide-angle colonoscopy in colorectal cancer screening
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spelling pubmed-81937432021-06-15 Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial Bogacki, Paweł Gach, Tomasz Krzak, Jan Szura, Miroslaw Wideochir Inne Tech Maloinwazyjne Original Paper INTRODUCTION: Colonoscopy is considered the gold standard for colorectal cancer screening. Panoramic colonoscopy offers better visualization to decrease the adenoma miss rate. AIM: To assess the influence of 330° panoramic view colonoscopy on adenoma and polyp detection rate, cecal intubation time, and examiner’s comfort. MATERIAL AND METHODS: The study enrolled 421 patients aged 18–80 years who were eligible for colonoscopy screening. Patients with prior abdominal surgery, inflammatory bowel disease or after colorectal resections were excluded from the study. Patients were randomized to either standard frontal view (SFV) (Olympus Evis Exera III 190 CF-HQ190L) or the panoramic view colonoscopy (PVC) (FUSE CDVL slim c38). The study was approved by the local bioethics committee and registered at ClinicalTrial.gov (NCT02929381). RESULTS: There were 214 patients examined with SFV and 207 with PVC. The mean age of patients was 64 ±12.26 years. The two groups were comparable. The median cecal intubation time was 234 s with SFV vs. 311 s with PVC (p < 0.001). There were no significant differences in CIR or withdrawal time. PVC made it possible to discover more diverticula in the ascending colon (p = 0.009). PDR with SFV was 34.6% and 40.1% with PVC (p = 0.242). A higher number of polyps was found in the transverse colon in the PVC group (p = 0.006). ADR and advanced ADR (aADR) in both groups were similar (26.4% vs. 27.1% and 14, 2% vs. 13.9%). CONCLUSIONS: Colonoscopy with wide-angle endoscopes lasts longer and allows for the detection of more polyps and diverticula without affecting ADR and aADR. Our study did not reveal the superiority of wide-angle colonoscopy in colorectal cancer screening Termedia Publishing House 2021-02-25 2021-06 /pmc/articles/PMC8193743/ /pubmed/34136023 http://dx.doi.org/10.5114/wiitm.2021.103922 Text en Copyright: © 2021 Fundacja Videochirurgii https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Bogacki, Paweł
Gach, Tomasz
Krzak, Jan
Szura, Miroslaw
Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title_full Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title_fullStr Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title_full_unstemmed Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title_short Panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
title_sort panoramic colonoscopy in colorectal cancer screening – a randomized controlled trial
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193743/
https://www.ncbi.nlm.nih.gov/pubmed/34136023
http://dx.doi.org/10.5114/wiitm.2021.103922
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AT szuramiroslaw panoramiccolonoscopyincolorectalcancerscreeningarandomizedcontrolledtrial