SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats

BACKGROUND: How to obtain a small interfering RNA (siRNA) vector has become a moot point in recent years. Exosomes (Exo) show advantages of long survival time in vivo, high transmission efficiency, and easy penetration across the blood-spinal cord barrier, renowned as excellent carriers of bioactive...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Qu, Mingjia, Li, Lu, Liu, Tao, Lin, Miaoman, Yu, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193895/
https://www.ncbi.nlm.nih.gov/pubmed/34112262
http://dx.doi.org/10.1186/s13287-021-02401-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193895/
https://www.ncbi.nlm.nih.gov/pubmed/34112262
http://dx.doi.org/10.1186/s13287-021-02401-x

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