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SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats

BACKGROUND: How to obtain a small interfering RNA (siRNA) vector has become a moot point in recent years. Exosomes (Exo) show advantages of long survival time in vivo, high transmission efficiency, and easy penetration across the blood-spinal cord barrier, renowned as excellent carriers of bioactive...

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Detalles Bibliográficos
Autores principales:	Huang, Wei, Qu, Mingjia, Li, Lu, Liu, Tao, Lin, Miaoman, Yu, Xiaobing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193895/ https://www.ncbi.nlm.nih.gov/pubmed/34112262 http://dx.doi.org/10.1186/s13287-021-02401-x

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