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Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma

BACKGROUND: Glioma-associated microglia/macrophages (GAMs) markedly influence glioma progression. Under the influence of transforming growth factor beta (TGFB), GAMs are polarized toward a tumor-supportive phenotype. However, neither therapeutic targeting of GAM recruitment nor TGFB signaling demons...

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Detalles Bibliográficos
Autores principales:	Toedebusch, Ryan, Grodzki, Ana Cristina, Dickinson, Peter J, Woolard, Kevin, Vinson, Nicole, Sturges, Beverly, Snyder, John, Li, Chai-Fei, Nagasaka, Ori, Consales, Blaire, Vernau, Karen, Knipe, Marguerite, Murthy, Vishal, Lein, Pamela J, Toedebusch, Christine M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193901/ https://www.ncbi.nlm.nih.gov/pubmed/34131649 http://dx.doi.org/10.1093/noajnl/vdab062

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