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Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Activity in Acute Lymphoblastic Leukemia Cells in vitro and in vivo

Acute lymphoblastic leukemia (ALL) is an aggressive malignancy. Adults with ALL have more than 50% relapse rates. We have previously validated that overexpression of nucleophosmin (NPM) is involved in the multidrug resistance (MDR) development during ALL; and a synthetically engineered recombinant N...

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Detalles Bibliográficos
Autores principales:	Gan, Donghui, Chen, Yuwen, Wu, Zhengjun, Luo, Liping, Yirga, Shimuye Kalayu, Zhang, Na, Ye, Fu, Chen, Haijun, Hu, Jianda, Chen, Yingyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193937/ https://www.ncbi.nlm.nih.gov/pubmed/34122059 http://dx.doi.org/10.3389/fphar.2021.607755

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