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Approaching Protein Barriers: Emerging Mechanisms of Replication Pausing in Eukaryotes
During nuclear DNA replication multiprotein replisome machines have to jointly traverse and duplicate the total length of each chromosome during each cell cycle. At certain genomic locations replisomes encounter tight DNA-protein complexes and slow down. This fork pausing is an active process involv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194067/ https://www.ncbi.nlm.nih.gov/pubmed/34124054 http://dx.doi.org/10.3389/fcell.2021.672510 |