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Protective effects of sodium butyrate on rotavirus inducing endoplasmic reticulum stress-mediated apoptosis via PERK-eIF2α signaling pathway in IPEC-J2 cells
BACKGROUND: Rotavirus (RV) is a major pathogen that causes severe gastroenteritis in infants and young animals. Endoplasmic reticulum (ER) stress and subsequent apoptosis play pivotal role in virus infection. However, the protective mechanisms of intestinal damage caused by RV are poorly defined, es...
Autores principales: | Zhao, Ye, Hu, Ningming, Jiang, Qin, Zhu, Li, Zhang, Ming, Jiang, Jun, Xiong, Manyi, Yang, Mingxian, Yang, Jiandong, Shen, Linyuan, Zhang, Shunhua, Niu, Lili, Chen, Lei, Chen, Daiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194137/ https://www.ncbi.nlm.nih.gov/pubmed/34112268 http://dx.doi.org/10.1186/s40104-021-00592-0 |
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