Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

BACKGROUND: Most congenital heart defects (CHDs) result from complex interactions among genetic susceptibilities, epigenetic modifications, and maternal environmental exposures. Characterizing the complex relationship between genetic, epigenetic, and transcriptomic variation will enhance our underst...

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Detalles Bibliográficos
Autores principales: Li, Ming, Lyu, Chen, Huang, Manyan, Do, Catherine, Tycko, Benjamin, Lupo, Philip J., MacLeod, Stewart L., Randolph, Christopher E., Liu, Nianjun, Witte, John S., Hobbs, Charlotte A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194170/
https://www.ncbi.nlm.nih.gov/pubmed/34112112
http://dx.doi.org/10.1186/s12863-021-00975-2

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