Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathy

BACKGROUND: Myofibrillar myopathy in humans causes protein aggregation, degeneration, and weakness of skeletal muscle. In horses, myofibrillar myopathy is a late-onset disease of unknown origin characterized by poor performance, atrophy, myofibrillar disarray, and desmin aggregation in skeletal musc...

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Detalles Bibliográficos
Autores principales: Williams, Zoë J., Velez-Irizarry, Deborah, Gardner, Keri, Valberg, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194174/
https://www.ncbi.nlm.nih.gov/pubmed/34112090
http://dx.doi.org/10.1186/s12864-021-07758-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194174/
https://www.ncbi.nlm.nih.gov/pubmed/34112090
http://dx.doi.org/10.1186/s12864-021-07758-0

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