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A positive-feedback loop between HBx and ALKBH5 promotes hepatocellular carcinogenesis

BACKGROUND: Hepatitis B Virus (HBV) contributes to liver carcinogenesis via various epigenetic mechanisms. The newly defined epigenetics, epitranscriptomics regulation, has been reported to involve in multiple cancers including Hepatocellular Carcinoma (HCC). Our previous study found that HBx, HBV e...

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Detalles Bibliográficos
Autores principales: Qu, Siming, Jin, Li, Huang, Hanfei, Lin, Jie, Gao, Weiwu, Zeng, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194239/
https://www.ncbi.nlm.nih.gov/pubmed/34112124
http://dx.doi.org/10.1186/s12885-021-08449-5