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Protein citrullination as a source of cancer neoantigens
BACKGROUND: Citrulline post-translational modification of proteins is mediated by protein arginine deiminase (PADI) family members and has been associated with autoimmune diseases. The role of PADI-citrullinome in immune response in cancer has not been evaluated. We hypothesized that PADI-mediated c...
Autores principales: | Katayama, Hiroyuki, Kobayashi, Makoto, Irajizad, Ehsan, Sevillano, Alejandro M, Patel, Nikul, Mao, Xiangying, Rusling, Leona, Vykoukal, Jody, Cai, Yining, Hsiao, Fuchung, Yu, Chuan-Yih, Long, James, Liu, Jinsong, Esteva, Franscisco, Fahrmann, Johannes, Hanash, Sam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194337/ https://www.ncbi.nlm.nih.gov/pubmed/34112737 http://dx.doi.org/10.1136/jitc-2021-002549 |
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