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Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol
There is a close relationship between the gut microbiome and health in humans including regulation of immunity and energy metabolism. This study investigated differences in the gut microbiome of herdsmen from two regions: Hongyuan pasture in Sichuan and Xilingol pasture in Inner Mongolia. We found s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194741/ https://www.ncbi.nlm.nih.gov/pubmed/34136190 http://dx.doi.org/10.1002/fsn3.2290 |
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author | Yang, Chengcong Peng, Chuantao Jin, Hao You, Lijun Wang, Jiao Xu, Haiyan Sun, Zhihong |
author_facet | Yang, Chengcong Peng, Chuantao Jin, Hao You, Lijun Wang, Jiao Xu, Haiyan Sun, Zhihong |
author_sort | Yang, Chengcong |
collection | PubMed |
description | There is a close relationship between the gut microbiome and health in humans including regulation of immunity and energy metabolism. This study investigated differences in the gut microbiome of herdsmen from two regions: Hongyuan pasture in Sichuan and Xilingol pasture in Inner Mongolia. We found significant differences in the gut microbiome between the two groups. The main discriminatory species between the two groups were Bifidobacterium longum, Bifidobacterium breve, Phascolarctobacterium succinatutens, Prevotella stercorea, Prevotella copri, Eubacterium biforme, and Fusobacterium prausnitzii. The abundances of Bifidobacterium longum and Bifidobacterium breve were significantly lower in the gut microbiomes of Hongyuan herdsmen than in the gut microbiomes of Xilingol herdsmen. Functional metagenomic analysis showed that more genes were enriched in glycoside hydrolase and transposase in the gut microbiome of Hongyuan herdsmen compared with Xilingol herdsmen, suggesting a higher energy demand in the gut microbiome of Hongyuan herdsmen. Significantly more genes associated with glycolysis, starch degradation, and sucrose degradation were also found in the gut microbiome of Hong yuan herdsmen compared with Xilingol herdsmen. These results indicate that herdsmen from different pastoral regions had distinct gut microbiome composition and functions. |
format | Online Article Text |
id | pubmed-8194741 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81947412021-06-15 Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol Yang, Chengcong Peng, Chuantao Jin, Hao You, Lijun Wang, Jiao Xu, Haiyan Sun, Zhihong Food Sci Nutr Original Research There is a close relationship between the gut microbiome and health in humans including regulation of immunity and energy metabolism. This study investigated differences in the gut microbiome of herdsmen from two regions: Hongyuan pasture in Sichuan and Xilingol pasture in Inner Mongolia. We found significant differences in the gut microbiome between the two groups. The main discriminatory species between the two groups were Bifidobacterium longum, Bifidobacterium breve, Phascolarctobacterium succinatutens, Prevotella stercorea, Prevotella copri, Eubacterium biforme, and Fusobacterium prausnitzii. The abundances of Bifidobacterium longum and Bifidobacterium breve were significantly lower in the gut microbiomes of Hongyuan herdsmen than in the gut microbiomes of Xilingol herdsmen. Functional metagenomic analysis showed that more genes were enriched in glycoside hydrolase and transposase in the gut microbiome of Hongyuan herdsmen compared with Xilingol herdsmen, suggesting a higher energy demand in the gut microbiome of Hongyuan herdsmen. Significantly more genes associated with glycolysis, starch degradation, and sucrose degradation were also found in the gut microbiome of Hong yuan herdsmen compared with Xilingol herdsmen. These results indicate that herdsmen from different pastoral regions had distinct gut microbiome composition and functions. John Wiley and Sons Inc. 2021-05-04 /pmc/articles/PMC8194741/ /pubmed/34136190 http://dx.doi.org/10.1002/fsn3.2290 Text en © 2021 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Yang, Chengcong Peng, Chuantao Jin, Hao You, Lijun Wang, Jiao Xu, Haiyan Sun, Zhihong Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title | Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title_full | Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title_fullStr | Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title_full_unstemmed | Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title_short | Comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, Hongyuan and Xilingol |
title_sort | comparison of the composition and function of the gut microbiome in herdsmen from two pasture regions, hongyuan and xilingol |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194741/ https://www.ncbi.nlm.nih.gov/pubmed/34136190 http://dx.doi.org/10.1002/fsn3.2290 |
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