Arginine methylation of APE1 promotes its mitochondrial translocation to protect cells from oxidative damage

Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential multifunctional protein in mammals that plays critical roles in DNA repair and redox signaling within the cell. Impaired APE1 function or dysregulation is associated with disease susceptibility and poor cancer prognosis. Orchestrated regula...

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Detalles Bibliográficos
Autores principales: Zhang, Yilan, Zhang, Qi, Li, LuLu, Mu, Dan, Hua, Ke, Ci, Shusheng, Shen, Lei, Zheng, Li, Shen, Binghui, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195256/
https://www.ncbi.nlm.nih.gov/pubmed/32679368
http://dx.doi.org/10.1016/j.freeradbiomed.2020.06.027

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