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Favipiravir-resistant influenza A virus shows potential for transmission
Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage in presence of drug with two mutations: K229R in PB1, which conferred resistance at a cost t...
Autores principales: | Goldhill, Daniel H., Yan, Ada, Frise, Rebecca, Zhou, Jie, Shelley, Jennifer, Gallego Cortés, Ana, Miah, Shahjahan, Akinbami, Omolola, Galiano, Monica, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195362/ https://www.ncbi.nlm.nih.gov/pubmed/34061908 http://dx.doi.org/10.1371/journal.ppat.1008937 |
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