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Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

BACKGROUND: Helminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria vaccine candidate, a recombinant protein consisti...

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Detalles Bibliográficos
Autores principales: Nouatin, Odilon, Mengue, Juliana Boex, Dejon-Agobé, Jean Claude, Fendel, Rolf, Ibáñez, Javier, Ngoa, Ulysse Ateba, Edoa, Jean Ronald, Adégbité, Bayodé Roméo, Honkpéhédji, Yabo Josiane, Zinsou, Jeannot Fréjus, Hounkpatin, Aurore Bouyoukou, Moutairou, Kabirou, Homoet, Andreas, Esen, Meral, Kreidenweiss, Andrea, Hoffman, Stephen L., Theisen, Michael, Luty, Adrian J. F., Lell, Bertrand, Agnandji, Selidji Todagbe, Mombo-Ngoma, Ghyslain, Ramharter, Michael, Kremsner, Peter, Mordmüller, Benjamin, Adegnika, Ayôla Akim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195366/
https://www.ncbi.nlm.nih.gov/pubmed/34061838
http://dx.doi.org/10.1371/journal.pntd.0009361

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