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A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1
The acoustic startle response is an evolutionarily conserved avoidance behavior. Disruptions in startle behavior, particularly startle magnitude, are a hallmark of several human neurological disorders. While the neural circuitry underlying startle behavior has been studied extensively, the repertoir...
Autores principales: | Meserve, Joy H., Nelson, Jessica C., Marsden, Kurt C., Hsu, Jerry, Echeverry, Fabio A., Jain, Roshan A., Wolman, Marc A., Pereda, Alberto E., Granato, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195410/ https://www.ncbi.nlm.nih.gov/pubmed/34061829 http://dx.doi.org/10.1371/journal.pgen.1008943 |
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