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CYTOPLASMIC-MEMBRANE EGFR PREDICTS EXPANDED RAS MUTATION STATUS IN COLORECTAL CARCINOMAS?
BACKGROUND: Inhibitors of the epidermal growth factor (EGFR) represent an effective therapeutic option for patients with metastatic colorectal carcinoma, free of activating mutations in KRAS and NRAS. However, the research of mutations is of high cost and scarcely accessible. The expression of the E...
Autores principales: | PINTO, Thiago David Alves, ALVES, Thaís David das Neves, PINTO, Sebastião Alves, OLIVEIRA, Enio Chaves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgia Digestiva
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195465/ https://www.ncbi.nlm.nih.gov/pubmed/34133521 http://dx.doi.org/10.1590/0102-672020210001e1574 |
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