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BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgia Digestiva
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195467/ https://www.ncbi.nlm.nih.gov/pubmed/34133523 http://dx.doi.org/10.1590/0102-672020210001e1576 |
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author | TORTEROLLI, Fernando WATANABE, Rafael Katsunori TABUSHI, Fernando Issamu PEIXOTO, Igor Luna NASSIF, Paulo Afonso Nunes TEFILLI, Nertan Luiz ROCHA, Sergio Luiz MALAFAIA, Osvaldo |
author_facet | TORTEROLLI, Fernando WATANABE, Rafael Katsunori TABUSHI, Fernando Issamu PEIXOTO, Igor Luna NASSIF, Paulo Afonso Nunes TEFILLI, Nertan Luiz ROCHA, Sergio Luiz MALAFAIA, Osvaldo |
author_sort | TORTEROLLI, Fernando |
collection | PubMed |
description | BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. METHOD: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results : The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). CONCLUSION: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective. |
format | Online Article Text |
id | pubmed-8195467 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Colégio Brasileiro de Cirurgia Digestiva |
record_format | MEDLINE/PubMed |
spelling | pubmed-81954672021-06-24 BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? TORTEROLLI, Fernando WATANABE, Rafael Katsunori TABUSHI, Fernando Issamu PEIXOTO, Igor Luna NASSIF, Paulo Afonso Nunes TEFILLI, Nertan Luiz ROCHA, Sergio Luiz MALAFAIA, Osvaldo Arq Bras Cir Dig Original Article BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. METHOD: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results : The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). CONCLUSION: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective. Colégio Brasileiro de Cirurgia Digestiva 2021-06-11 /pmc/articles/PMC8195467/ /pubmed/34133523 http://dx.doi.org/10.1590/0102-672020210001e1576 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article TORTEROLLI, Fernando WATANABE, Rafael Katsunori TABUSHI, Fernando Issamu PEIXOTO, Igor Luna NASSIF, Paulo Afonso Nunes TEFILLI, Nertan Luiz ROCHA, Sergio Luiz MALAFAIA, Osvaldo BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title | BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title_full | BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title_fullStr | BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title_full_unstemmed | BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title_short | BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? |
title_sort | bar, soft and dri post-hepatic transplantation: what is the best for survival analysis? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195467/ https://www.ncbi.nlm.nih.gov/pubmed/34133523 http://dx.doi.org/10.1590/0102-672020210001e1576 |
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