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BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?

BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the...

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Autores principales: TORTEROLLI, Fernando, WATANABE, Rafael Katsunori, TABUSHI, Fernando Issamu, PEIXOTO, Igor Luna, NASSIF, Paulo Afonso Nunes, TEFILLI, Nertan Luiz, ROCHA, Sergio Luiz, MALAFAIA, Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195467/
https://www.ncbi.nlm.nih.gov/pubmed/34133523
http://dx.doi.org/10.1590/0102-672020210001e1576
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author TORTEROLLI, Fernando
WATANABE, Rafael Katsunori
TABUSHI, Fernando Issamu
PEIXOTO, Igor Luna
NASSIF, Paulo Afonso Nunes
TEFILLI, Nertan Luiz
ROCHA, Sergio Luiz
MALAFAIA, Osvaldo
author_facet TORTEROLLI, Fernando
WATANABE, Rafael Katsunori
TABUSHI, Fernando Issamu
PEIXOTO, Igor Luna
NASSIF, Paulo Afonso Nunes
TEFILLI, Nertan Luiz
ROCHA, Sergio Luiz
MALAFAIA, Osvaldo
author_sort TORTEROLLI, Fernando
collection PubMed
description BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. METHOD: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results : The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). CONCLUSION: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective.
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spelling pubmed-81954672021-06-24 BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS? TORTEROLLI, Fernando WATANABE, Rafael Katsunori TABUSHI, Fernando Issamu PEIXOTO, Igor Luna NASSIF, Paulo Afonso Nunes TEFILLI, Nertan Luiz ROCHA, Sergio Luiz MALAFAIA, Osvaldo Arq Bras Cir Dig Original Article BACKGROUND: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. AIM: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. METHOD: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results : The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). CONCLUSION: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective. Colégio Brasileiro de Cirurgia Digestiva 2021-06-11 /pmc/articles/PMC8195467/ /pubmed/34133523 http://dx.doi.org/10.1590/0102-672020210001e1576 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
TORTEROLLI, Fernando
WATANABE, Rafael Katsunori
TABUSHI, Fernando Issamu
PEIXOTO, Igor Luna
NASSIF, Paulo Afonso Nunes
TEFILLI, Nertan Luiz
ROCHA, Sergio Luiz
MALAFAIA, Osvaldo
BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title_full BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title_fullStr BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title_full_unstemmed BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title_short BAR, SOFT AND DRI POST-HEPATIC TRANSPLANTATION: WHAT IS THE BEST FOR SURVIVAL ANALYSIS?
title_sort bar, soft and dri post-hepatic transplantation: what is the best for survival analysis?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195467/
https://www.ncbi.nlm.nih.gov/pubmed/34133523
http://dx.doi.org/10.1590/0102-672020210001e1576
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