Polarized endosome dynamics engage cytoplasmic Par-3 that recruits dynein during asymmetric cell division

In the developing embryos, the cortical polarity regulator Par-3 is critical for establishing Notch signaling asymmetry between daughter cells during asymmetric cell division (ACD). How cortically localized Par-3 establishes asymmetric Notch activity in the nucleus is not understood. Here, using in...

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Detalles Bibliográficos
Autores principales: Zhao, Xiang, Garcia, Jason Q., Tong, Kai, Chen, Xingye, Yang, Bin, Li, Qi, Dai, Zhipeng, Shi, Xiaoyu, Seiple, Ian B., Huang, Bo, Guo, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195473/
https://www.ncbi.nlm.nih.gov/pubmed/34117063
http://dx.doi.org/10.1126/sciadv.abg1244

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