A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis

Transcoelomic spread of cancer cells across the peritoneal cavity occurs in most initially diagnosed ovarian cancer (OC) patients and accounts for most cancer-related death. However, how OC cells interact with peritoneal stromal cells to evade the immune surveillance remains largely unexplored. Here...

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Detalles Bibliográficos
Autores principales: Li, Jia, Qin, Xuan, Shi, Jie, Wang, Xiaoshuang, Li, Tong, Xu, Mengyao, Chen, Xiaosu, Zhao, Yujia, Han, Jiahao, Piao, Yongjun, Zhang, Wenwen, Qu, Pengpeng, Wang, Longlong, Xiang, Rong, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195602/
https://www.ncbi.nlm.nih.gov/pubmed/34114949
http://dx.doi.org/10.7554/eLife.66222

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