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Synthetic biology approaches to actinomycete strain improvement
Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synt...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195692/ https://www.ncbi.nlm.nih.gov/pubmed/34057181 http://dx.doi.org/10.1093/femsle/fnab060 |
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| author | Breitling, Rainer Avbelj, Martina Bilyk, Oksana Carratore, Francesco Del Filisetti, Alessandro Hanko, Erik K R Iorio, Marianna Redondo, Rosario Pérez Reyes, Fernando Rudden, Michelle Severi, Emmanuele Slemc, Lucija Schmidt, Kamila Whittall, Dominic R Donadio, Stefano García, Antonio Rodríguez Genilloud, Olga Kosec, Gregor De Lucrezia, Davide Petković, Hrvoje Thomas, Gavin Takano, Eriko |
| author_facet | Breitling, Rainer Avbelj, Martina Bilyk, Oksana Carratore, Francesco Del Filisetti, Alessandro Hanko, Erik K R Iorio, Marianna Redondo, Rosario Pérez Reyes, Fernando Rudden, Michelle Severi, Emmanuele Slemc, Lucija Schmidt, Kamila Whittall, Dominic R Donadio, Stefano García, Antonio Rodríguez Genilloud, Olga Kosec, Gregor De Lucrezia, Davide Petković, Hrvoje Thomas, Gavin Takano, Eriko |
| author_sort | Breitling, Rainer |
| collection | PubMed |
| description | Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains. |
| format | Online Article Text |
| id | pubmed-8195692 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-81956922021-06-14 Synthetic biology approaches to actinomycete strain improvement Breitling, Rainer Avbelj, Martina Bilyk, Oksana Carratore, Francesco Del Filisetti, Alessandro Hanko, Erik K R Iorio, Marianna Redondo, Rosario Pérez Reyes, Fernando Rudden, Michelle Severi, Emmanuele Slemc, Lucija Schmidt, Kamila Whittall, Dominic R Donadio, Stefano García, Antonio Rodríguez Genilloud, Olga Kosec, Gregor De Lucrezia, Davide Petković, Hrvoje Thomas, Gavin Takano, Eriko FEMS Microbiol Lett Minireview Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains. Oxford University Press 2021-05-31 /pmc/articles/PMC8195692/ /pubmed/34057181 http://dx.doi.org/10.1093/femsle/fnab060 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of FEMS. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Minireview Breitling, Rainer Avbelj, Martina Bilyk, Oksana Carratore, Francesco Del Filisetti, Alessandro Hanko, Erik K R Iorio, Marianna Redondo, Rosario Pérez Reyes, Fernando Rudden, Michelle Severi, Emmanuele Slemc, Lucija Schmidt, Kamila Whittall, Dominic R Donadio, Stefano García, Antonio Rodríguez Genilloud, Olga Kosec, Gregor De Lucrezia, Davide Petković, Hrvoje Thomas, Gavin Takano, Eriko Synthetic biology approaches to actinomycete strain improvement |
| title | Synthetic biology approaches to actinomycete strain improvement |
| title_full | Synthetic biology approaches to actinomycete strain improvement |
| title_fullStr | Synthetic biology approaches to actinomycete strain improvement |
| title_full_unstemmed | Synthetic biology approaches to actinomycete strain improvement |
| title_short | Synthetic biology approaches to actinomycete strain improvement |
| title_sort | synthetic biology approaches to actinomycete strain improvement |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195692/ https://www.ncbi.nlm.nih.gov/pubmed/34057181 http://dx.doi.org/10.1093/femsle/fnab060 |
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