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Avasimibe Dampens Cholangiocarcinoma Progression by Inhibiting FoxM1-AKR1C1 Signaling

Avasimibe is a bioavailable acetyl-CoA acetyltransferase (ACAT) inhibitor and shows a good antitumor effect in various human solid tumors, but its therapeutic value in cholangiocarcinoma (CCA) and underlying mechanisms are largely unknown. In the study, we proved that avasimibe retard cell prolifera...

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Detalles Bibliográficos
Autores principales:	Gao, Yunshu, Xu, Dongyun, Li, Hongwei, Xu, Jiahua, Pan, Yating, Liao, Xinyi, Qian, Jianxin, Hu, Yi, Yu, Guanzhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195695/ https://www.ncbi.nlm.nih.gov/pubmed/34127944 http://dx.doi.org/10.3389/fonc.2021.677678

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