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USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response
The Ubiquitin-Specific Protease 22 (USP22) is a deubiquitinating subunit of the mammalian SAGA transcriptional co-activating complex. USP22 was identified as a member of the so-called “death-from-cancer” signature predicting therapy failure in cancer patients. However, the importance and functional...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195738/ https://www.ncbi.nlm.nih.gov/pubmed/34007022 http://dx.doi.org/10.1038/s41388-021-01814-5 |