Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma

The tumor microenvironment is deeply involved in the process of tumor growth and development. In this study, we focused on cancer-associated fibroblasts (CAFs) and their derived exosomes on the lymphoma microenvironment to uncover their clinical significance. CAFs were established from primary lymph...

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Detalles Bibliográficos
Autores principales: Kunou, Shunsuke, Shimada, Kazuyuki, Takai, Mika, Sakamoto, Akihiko, Aoki, Tomohiro, Hikita, Tomoya, Kagaya, Yusuke, Iwamoto, Eisuke, Sanada, Masashi, Shimada, Satoko, Hayakawa, Fumihiko, Oneyama, Chitose, Kiyoi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195743/
https://www.ncbi.nlm.nih.gov/pubmed/33994542
http://dx.doi.org/10.1038/s41388-021-01829-y

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