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Assessing Single-Cell Transcriptomic Variability through Density-Preserving Data Visualization

Nonlinear data-visualization methods, such as t-SNE and UMAP, summarize the complex transcriptomic landscape of single cells in 2D or 3D, but they neglect the local density of data points in the original space, often resulting in misleading visualizations where densely populated subsets of cells are...

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Detalles Bibliográficos
Autores principales: Narayan, Ashwin, Berger, Bonnie, Cho, Hyunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195812/
https://www.ncbi.nlm.nih.gov/pubmed/33462509
http://dx.doi.org/10.1038/s41587-020-00801-7

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