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Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients

Immune checkpoint inhibitors (ICI) are designed to activate exhausted tumor-reactive T cells thereby leading to tumor regression. Durvalumab, an ICI that binds to the programmed death ligand-1 (PD-L1) molecule, is approved as a consolidation therapy for treatment of patients with stage III, unresect...

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Detalles Bibliográficos
Autores principales:	Naidus, Elliot, Bouquet, Jerome, Oh, David Y., Looney, Timothy J., Yang, Hai, Fong, Lawrence, Standifer, Nathan E., Zhang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195930/ https://www.ncbi.nlm.nih.gov/pubmed/33420629 http://dx.doi.org/10.1007/s00262-020-02833-z

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