Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts

The transcriptional repressor Rev-erbα is known to down-regulate fatty acid metabolism and gluconeogenesis gene expression. In animal models, disruption of Rev-erbα results in global changes in exercise performance, oxidative capacity, and blood glucose levels. However, the complete extent to which...

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Detalles Bibliográficos
Autores principales: Gillis, Sean P., Yao, Hongwei, Rizal, Salu, Maeda, Hajime, Chang, Julia, Dennery, Phyllis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196003/
https://www.ncbi.nlm.nih.gov/pubmed/34117285
http://dx.doi.org/10.1038/s41598-021-91516-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196003/
https://www.ncbi.nlm.nih.gov/pubmed/34117285
http://dx.doi.org/10.1038/s41598-021-91516-5

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