SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung

There is a great need for the development of vaccines that induce potent and long-lasting protective immunity against SARS-CoV-2. Multimeric display of the antigen combined with potent adjuvant can enhance the potency and longevity of the antibody response. The receptor binding domain (RBD) of the s...

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Detalles Bibliográficos
Autores principales: Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Bollimpelli, Venkata Satish, Gangadhara, Sailaja, Edara, Venkata Viswanadh, Lai, Lilin, Sahoo, Anusmita, Shiferaw, Ayalnesh, Styles, Tiffany M., Floyd, Katharine, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Dinnon, Kenneth H., Shi, Pei-Yong, Menachery, Vineet D., Tomai, Mark, Fox, Christopher B., Alter, Galit, Vanderford, Thomas H., Gralinski, Lisa, Suthar, Mehul S., Amara, Rama Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196016/
https://www.ncbi.nlm.nih.gov/pubmed/34117252
http://dx.doi.org/10.1038/s41467-021-23942-y

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