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Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report
Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196041/ https://www.ncbi.nlm.nih.gov/pubmed/34159057 http://dx.doi.org/10.1016/j.crwh.2021.e00332 |
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author | Chae-Kim, Jennifer J. Roman, Robert Hawkins, Kristina Gavrilova-Jordan, Larisa |
author_facet | Chae-Kim, Jennifer J. Roman, Robert Hawkins, Kristina Gavrilova-Jordan, Larisa |
author_sort | Chae-Kim, Jennifer J. |
collection | PubMed |
description | Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum levels of anti-Müllerian hormone (AMH), large number of recruited follicles, elevated serum levels of estradiol, and higher gonadotropin doses during COS. However, OHSS may develop in patients with minimal risk factors. We present the case of a patient with minimal risk factors who developed severe late-onset OHSS in early pregnancy with liver dysfunction requiring hospitalization. After hospital discharge, her pregnancy resulted in a term live birth. We recommend that clinicians include OHSS in the differential diagnosis of elevated levels of liver enzymes in early pregnancy. |
format | Online Article Text |
id | pubmed-8196041 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81960412021-06-21 Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report Chae-Kim, Jennifer J. Roman, Robert Hawkins, Kristina Gavrilova-Jordan, Larisa Case Rep Womens Health Article Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum levels of anti-Müllerian hormone (AMH), large number of recruited follicles, elevated serum levels of estradiol, and higher gonadotropin doses during COS. However, OHSS may develop in patients with minimal risk factors. We present the case of a patient with minimal risk factors who developed severe late-onset OHSS in early pregnancy with liver dysfunction requiring hospitalization. After hospital discharge, her pregnancy resulted in a term live birth. We recommend that clinicians include OHSS in the differential diagnosis of elevated levels of liver enzymes in early pregnancy. Elsevier 2021-06-04 /pmc/articles/PMC8196041/ /pubmed/34159057 http://dx.doi.org/10.1016/j.crwh.2021.e00332 Text en © 2021 Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Chae-Kim, Jennifer J. Roman, Robert Hawkins, Kristina Gavrilova-Jordan, Larisa Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title | Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title_full | Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title_fullStr | Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title_full_unstemmed | Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title_short | Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report |
title_sort | severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196041/ https://www.ncbi.nlm.nih.gov/pubmed/34159057 http://dx.doi.org/10.1016/j.crwh.2021.e00332 |
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