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A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies

A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these f...

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Autores principales: Nagata, Jun, Kawasaki, Takeshi, Iesato, Ken, Sugiura, Toshihiko, Yamauchi, Keita, Tsuyusaki, Junichi, Fujimura, Masaaki, Kuroda, Fuminobu, Mikami, Kazuo, Dudek, Steven M., Tanabe, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196048/
https://www.ncbi.nlm.nih.gov/pubmed/34159054
http://dx.doi.org/10.1016/j.idcr.2021.e01176
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author Nagata, Jun
Kawasaki, Takeshi
Iesato, Ken
Sugiura, Toshihiko
Yamauchi, Keita
Tsuyusaki, Junichi
Fujimura, Masaaki
Kuroda, Fuminobu
Mikami, Kazuo
Dudek, Steven M.
Tanabe, Nobuhiro
author_facet Nagata, Jun
Kawasaki, Takeshi
Iesato, Ken
Sugiura, Toshihiko
Yamauchi, Keita
Tsuyusaki, Junichi
Fujimura, Masaaki
Kuroda, Fuminobu
Mikami, Kazuo
Dudek, Steven M.
Tanabe, Nobuhiro
author_sort Nagata, Jun
collection PubMed
description A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these findings, the patient was diagnosed with candidemia that developed due to Candida urinary tract infection, complicated by septic pulmonary embolism and severe diabetes mellitus. Candidemia likely persisted despite the initiation of intravenous antifungal therapy and control of blood sugar level. Therefore, surgical removal of the urethral foreign bodies was performed, which resulted in resolution of the patient’s symptoms. Herein, we report a rare case of candidemia complicated by Candida urinary tract infection that developed due to the long-term presence of urethral foreign bodies. A multidisciplinary therapeutic approach, including surgical removal of the infected foreign bodies, is effective in such cases. This case indicates that long-term presence of foreign bodies and acquired immune dysfunction can be risk factors for candidemia. Therefore, detailed history should be obtained and systemic examination should be performed to identify the complicating risk factors on diagnosis of candidemia.
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spelling pubmed-81960482021-06-21 A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies Nagata, Jun Kawasaki, Takeshi Iesato, Ken Sugiura, Toshihiko Yamauchi, Keita Tsuyusaki, Junichi Fujimura, Masaaki Kuroda, Fuminobu Mikami, Kazuo Dudek, Steven M. Tanabe, Nobuhiro IDCases Case Report A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these findings, the patient was diagnosed with candidemia that developed due to Candida urinary tract infection, complicated by septic pulmonary embolism and severe diabetes mellitus. Candidemia likely persisted despite the initiation of intravenous antifungal therapy and control of blood sugar level. Therefore, surgical removal of the urethral foreign bodies was performed, which resulted in resolution of the patient’s symptoms. Herein, we report a rare case of candidemia complicated by Candida urinary tract infection that developed due to the long-term presence of urethral foreign bodies. A multidisciplinary therapeutic approach, including surgical removal of the infected foreign bodies, is effective in such cases. This case indicates that long-term presence of foreign bodies and acquired immune dysfunction can be risk factors for candidemia. Therefore, detailed history should be obtained and systemic examination should be performed to identify the complicating risk factors on diagnosis of candidemia. Elsevier 2021-06-08 /pmc/articles/PMC8196048/ /pubmed/34159054 http://dx.doi.org/10.1016/j.idcr.2021.e01176 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nagata, Jun
Kawasaki, Takeshi
Iesato, Ken
Sugiura, Toshihiko
Yamauchi, Keita
Tsuyusaki, Junichi
Fujimura, Masaaki
Kuroda, Fuminobu
Mikami, Kazuo
Dudek, Steven M.
Tanabe, Nobuhiro
A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title_full A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title_fullStr A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title_full_unstemmed A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title_short A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
title_sort case of candidemia after long-term presence of urethral foreign bodies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196048/
https://www.ncbi.nlm.nih.gov/pubmed/34159054
http://dx.doi.org/10.1016/j.idcr.2021.e01176
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