Cargando…
A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies
A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these f...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196048/ https://www.ncbi.nlm.nih.gov/pubmed/34159054 http://dx.doi.org/10.1016/j.idcr.2021.e01176 |
_version_ | 1783706612090798080 |
---|---|
author | Nagata, Jun Kawasaki, Takeshi Iesato, Ken Sugiura, Toshihiko Yamauchi, Keita Tsuyusaki, Junichi Fujimura, Masaaki Kuroda, Fuminobu Mikami, Kazuo Dudek, Steven M. Tanabe, Nobuhiro |
author_facet | Nagata, Jun Kawasaki, Takeshi Iesato, Ken Sugiura, Toshihiko Yamauchi, Keita Tsuyusaki, Junichi Fujimura, Masaaki Kuroda, Fuminobu Mikami, Kazuo Dudek, Steven M. Tanabe, Nobuhiro |
author_sort | Nagata, Jun |
collection | PubMed |
description | A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these findings, the patient was diagnosed with candidemia that developed due to Candida urinary tract infection, complicated by septic pulmonary embolism and severe diabetes mellitus. Candidemia likely persisted despite the initiation of intravenous antifungal therapy and control of blood sugar level. Therefore, surgical removal of the urethral foreign bodies was performed, which resulted in resolution of the patient’s symptoms. Herein, we report a rare case of candidemia complicated by Candida urinary tract infection that developed due to the long-term presence of urethral foreign bodies. A multidisciplinary therapeutic approach, including surgical removal of the infected foreign bodies, is effective in such cases. This case indicates that long-term presence of foreign bodies and acquired immune dysfunction can be risk factors for candidemia. Therefore, detailed history should be obtained and systemic examination should be performed to identify the complicating risk factors on diagnosis of candidemia. |
format | Online Article Text |
id | pubmed-8196048 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81960482021-06-21 A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies Nagata, Jun Kawasaki, Takeshi Iesato, Ken Sugiura, Toshihiko Yamauchi, Keita Tsuyusaki, Junichi Fujimura, Masaaki Kuroda, Fuminobu Mikami, Kazuo Dudek, Steven M. Tanabe, Nobuhiro IDCases Case Report A 52-year-old man presented to our hospital complaining of general malaise, cough, and fever. Total body computed tomography revealed scattered pneumonia and urethral foreign bodies that had been inserted during adolescence. Candida glabrata was detected in blood and urine cultures. Based on these findings, the patient was diagnosed with candidemia that developed due to Candida urinary tract infection, complicated by septic pulmonary embolism and severe diabetes mellitus. Candidemia likely persisted despite the initiation of intravenous antifungal therapy and control of blood sugar level. Therefore, surgical removal of the urethral foreign bodies was performed, which resulted in resolution of the patient’s symptoms. Herein, we report a rare case of candidemia complicated by Candida urinary tract infection that developed due to the long-term presence of urethral foreign bodies. A multidisciplinary therapeutic approach, including surgical removal of the infected foreign bodies, is effective in such cases. This case indicates that long-term presence of foreign bodies and acquired immune dysfunction can be risk factors for candidemia. Therefore, detailed history should be obtained and systemic examination should be performed to identify the complicating risk factors on diagnosis of candidemia. Elsevier 2021-06-08 /pmc/articles/PMC8196048/ /pubmed/34159054 http://dx.doi.org/10.1016/j.idcr.2021.e01176 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Nagata, Jun Kawasaki, Takeshi Iesato, Ken Sugiura, Toshihiko Yamauchi, Keita Tsuyusaki, Junichi Fujimura, Masaaki Kuroda, Fuminobu Mikami, Kazuo Dudek, Steven M. Tanabe, Nobuhiro A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title | A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title_full | A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title_fullStr | A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title_full_unstemmed | A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title_short | A Case of Candidemia after Long-term Presence of Urethral Foreign Bodies |
title_sort | case of candidemia after long-term presence of urethral foreign bodies |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196048/ https://www.ncbi.nlm.nih.gov/pubmed/34159054 http://dx.doi.org/10.1016/j.idcr.2021.e01176 |
work_keys_str_mv | AT nagatajun acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT kawasakitakeshi acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT iesatoken acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT sugiuratoshihiko acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT yamauchikeita acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT tsuyusakijunichi acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT fujimuramasaaki acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT kurodafuminobu acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT mikamikazuo acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT dudekstevenm acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT tanabenobuhiro acaseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT nagatajun caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT kawasakitakeshi caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT iesatoken caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT sugiuratoshihiko caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT yamauchikeita caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT tsuyusakijunichi caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT fujimuramasaaki caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT kurodafuminobu caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT mikamikazuo caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT dudekstevenm caseofcandidemiaafterlongtermpresenceofurethralforeignbodies AT tanabenobuhiro caseofcandidemiaafterlongtermpresenceofurethralforeignbodies |