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An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization

INTRODUCTION AND IMPORTANCE: Fibrous Dysplasia (FD) is a benign fibro-osseous lesion, characterized by replacement with fibrous connective tissue instead of normal bone. The best treatment option for the condition has not yet been established, although several therapeutic approaches have been report...

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Autores principales: Bernaola-Paredes, Wilber E., Veronese, Henrique Rocha Mazorchi, de Andrade Celestino, Miriã, Martins, Ivan Solani, de Arruda, Arthur Ferrari, Vallejo-Rosero, Kleber A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196049/
https://www.ncbi.nlm.nih.gov/pubmed/34119940
http://dx.doi.org/10.1016/j.ijscr.2021.106049
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author Bernaola-Paredes, Wilber E.
Veronese, Henrique Rocha Mazorchi
de Andrade Celestino, Miriã
Martins, Ivan Solani
de Arruda, Arthur Ferrari
Vallejo-Rosero, Kleber A.
author_facet Bernaola-Paredes, Wilber E.
Veronese, Henrique Rocha Mazorchi
de Andrade Celestino, Miriã
Martins, Ivan Solani
de Arruda, Arthur Ferrari
Vallejo-Rosero, Kleber A.
author_sort Bernaola-Paredes, Wilber E.
collection PubMed
description INTRODUCTION AND IMPORTANCE: Fibrous Dysplasia (FD) is a benign fibro-osseous lesion, characterized by replacement with fibrous connective tissue instead of normal bone. The best treatment option for the condition has not yet been established, although several therapeutic approaches have been reported. The present case report describes the clinical, imaging and therapeutic aspects of an atypical bilateral presentation of FD in the mandible. CASE PRESENTATION: A 26-year-old afro-descendent woman, who had previously undergone surgery to remove FD in the right hemimandible, complained of asymptomatic swelling in the left hemimandible. Imaging analysis showed an ipsilateral extensive multilocular mandibular lesion, with thinning of the cortical bone. After diagnosis of FD, complete surgical removal was performed, associated with immediate local reconstruction with xenograft and covering membrane, with primary wound closure. CLINICAL DISCUSSION: Bilateral presentation of FD is uncommon, and its diagnosis by means of clinical data, imaging and histopathological analysis, is relevant in order to establish the correct therapy. CONCLUSION: Complete surgical removal associated with immediate local bone reconstruction, has shown satisfactory clinical results, when adequate follow-up is performed.
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spelling pubmed-81960492021-06-21 An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization Bernaola-Paredes, Wilber E. Veronese, Henrique Rocha Mazorchi de Andrade Celestino, Miriã Martins, Ivan Solani de Arruda, Arthur Ferrari Vallejo-Rosero, Kleber A. Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Fibrous Dysplasia (FD) is a benign fibro-osseous lesion, characterized by replacement with fibrous connective tissue instead of normal bone. The best treatment option for the condition has not yet been established, although several therapeutic approaches have been reported. The present case report describes the clinical, imaging and therapeutic aspects of an atypical bilateral presentation of FD in the mandible. CASE PRESENTATION: A 26-year-old afro-descendent woman, who had previously undergone surgery to remove FD in the right hemimandible, complained of asymptomatic swelling in the left hemimandible. Imaging analysis showed an ipsilateral extensive multilocular mandibular lesion, with thinning of the cortical bone. After diagnosis of FD, complete surgical removal was performed, associated with immediate local reconstruction with xenograft and covering membrane, with primary wound closure. CLINICAL DISCUSSION: Bilateral presentation of FD is uncommon, and its diagnosis by means of clinical data, imaging and histopathological analysis, is relevant in order to establish the correct therapy. CONCLUSION: Complete surgical removal associated with immediate local bone reconstruction, has shown satisfactory clinical results, when adequate follow-up is performed. Elsevier 2021-05-29 /pmc/articles/PMC8196049/ /pubmed/34119940 http://dx.doi.org/10.1016/j.ijscr.2021.106049 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Bernaola-Paredes, Wilber E.
Veronese, Henrique Rocha Mazorchi
de Andrade Celestino, Miriã
Martins, Ivan Solani
de Arruda, Arthur Ferrari
Vallejo-Rosero, Kleber A.
An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title_full An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title_fullStr An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title_full_unstemmed An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title_short An Atypical Bilateral Presentation of Fibrous Dysplasia (FD) in the Mandible: Clinical, imaging and therapeutic characterization
title_sort atypical bilateral presentation of fibrous dysplasia (fd) in the mandible: clinical, imaging and therapeutic characterization
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196049/
https://www.ncbi.nlm.nih.gov/pubmed/34119940
http://dx.doi.org/10.1016/j.ijscr.2021.106049
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