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Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma

BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a...

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Autores principales: Kuroki, Masahiro, Suzuki, Hiroto, Kurota, Misato, Nakane, Masaki, Kawamae, Kaneyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196126/
https://www.ncbi.nlm.nih.gov/pubmed/34117557
http://dx.doi.org/10.1186/s40981-021-00449-5
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author Kuroki, Masahiro
Suzuki, Hiroto
Kurota, Misato
Nakane, Masaki
Kawamae, Kaneyuki
author_facet Kuroki, Masahiro
Suzuki, Hiroto
Kurota, Misato
Nakane, Masaki
Kawamae, Kaneyuki
author_sort Kuroki, Masahiro
collection PubMed
description BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a sustained high fever with elevated serum noradrenaline and IL-6 levels. The persistent high inflammatory state, followed by anemia, malnutrition, and coagulopathy, led us to prepone her date of surgery. During general anesthesia, alpha-blockers allowed hemodynamic fluctuations to be controlled. During surgery, simultaneous increases in noradrenaline and IL-6 levels were observed, which rapidly declined after tumor removal. Her postoperative course was uneventful, without pulmonary edema caused by cytokine storms. CONCLUSIONS: The conventional pheochromocytoma strategy allowed surgical removal of an IL-6-producing pheochromocytoma under general anesthesia. However, management of high inflammatory states that induce anemia and coagulopathy is necessary.
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spelling pubmed-81961262021-06-28 Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma Kuroki, Masahiro Suzuki, Hiroto Kurota, Misato Nakane, Masaki Kawamae, Kaneyuki JA Clin Rep Case Report BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a sustained high fever with elevated serum noradrenaline and IL-6 levels. The persistent high inflammatory state, followed by anemia, malnutrition, and coagulopathy, led us to prepone her date of surgery. During general anesthesia, alpha-blockers allowed hemodynamic fluctuations to be controlled. During surgery, simultaneous increases in noradrenaline and IL-6 levels were observed, which rapidly declined after tumor removal. Her postoperative course was uneventful, without pulmonary edema caused by cytokine storms. CONCLUSIONS: The conventional pheochromocytoma strategy allowed surgical removal of an IL-6-producing pheochromocytoma under general anesthesia. However, management of high inflammatory states that induce anemia and coagulopathy is necessary. Springer Berlin Heidelberg 2021-06-11 /pmc/articles/PMC8196126/ /pubmed/34117557 http://dx.doi.org/10.1186/s40981-021-00449-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Kuroki, Masahiro
Suzuki, Hiroto
Kurota, Misato
Nakane, Masaki
Kawamae, Kaneyuki
Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title_full Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title_fullStr Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title_full_unstemmed Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title_short Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
title_sort perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196126/
https://www.ncbi.nlm.nih.gov/pubmed/34117557
http://dx.doi.org/10.1186/s40981-021-00449-5
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