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Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma
BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196126/ https://www.ncbi.nlm.nih.gov/pubmed/34117557 http://dx.doi.org/10.1186/s40981-021-00449-5 |
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author | Kuroki, Masahiro Suzuki, Hiroto Kurota, Misato Nakane, Masaki Kawamae, Kaneyuki |
author_facet | Kuroki, Masahiro Suzuki, Hiroto Kurota, Misato Nakane, Masaki Kawamae, Kaneyuki |
author_sort | Kuroki, Masahiro |
collection | PubMed |
description | BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a sustained high fever with elevated serum noradrenaline and IL-6 levels. The persistent high inflammatory state, followed by anemia, malnutrition, and coagulopathy, led us to prepone her date of surgery. During general anesthesia, alpha-blockers allowed hemodynamic fluctuations to be controlled. During surgery, simultaneous increases in noradrenaline and IL-6 levels were observed, which rapidly declined after tumor removal. Her postoperative course was uneventful, without pulmonary edema caused by cytokine storms. CONCLUSIONS: The conventional pheochromocytoma strategy allowed surgical removal of an IL-6-producing pheochromocytoma under general anesthesia. However, management of high inflammatory states that induce anemia and coagulopathy is necessary. |
format | Online Article Text |
id | pubmed-8196126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-81961262021-06-28 Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma Kuroki, Masahiro Suzuki, Hiroto Kurota, Misato Nakane, Masaki Kawamae, Kaneyuki JA Clin Rep Case Report BACKGROUND: Pheochromocytomas produce hormones, cytokines, and catecholamines. We report perioperative anesthetic management of a rare interleukin-6 (IL-6)-producing pheochromocytoma. CASE PRESENTATION: A 32-year-old female was scheduled for laparoscopic adrenalectomy for pheochromocytoma. She had a sustained high fever with elevated serum noradrenaline and IL-6 levels. The persistent high inflammatory state, followed by anemia, malnutrition, and coagulopathy, led us to prepone her date of surgery. During general anesthesia, alpha-blockers allowed hemodynamic fluctuations to be controlled. During surgery, simultaneous increases in noradrenaline and IL-6 levels were observed, which rapidly declined after tumor removal. Her postoperative course was uneventful, without pulmonary edema caused by cytokine storms. CONCLUSIONS: The conventional pheochromocytoma strategy allowed surgical removal of an IL-6-producing pheochromocytoma under general anesthesia. However, management of high inflammatory states that induce anemia and coagulopathy is necessary. Springer Berlin Heidelberg 2021-06-11 /pmc/articles/PMC8196126/ /pubmed/34117557 http://dx.doi.org/10.1186/s40981-021-00449-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Case Report Kuroki, Masahiro Suzuki, Hiroto Kurota, Misato Nakane, Masaki Kawamae, Kaneyuki Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title | Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title_full | Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title_fullStr | Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title_full_unstemmed | Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title_short | Perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
title_sort | perioperative management of a patient undergoing resection of interleukin-6 producing pheochromocytoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196126/ https://www.ncbi.nlm.nih.gov/pubmed/34117557 http://dx.doi.org/10.1186/s40981-021-00449-5 |
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