Cargando…
Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis
Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol. In previous studies, we demonstrated that Mtb...
Autores principales: | Pawełczyk, Jakub, Brzostek, Anna, Minias, Alina, Płociński, Przemysław, Rumijowska-Galewicz, Anna, Strapagiel, Dominik, Zakrzewska-Czerwińska, Jolanta, Dziadek, Jarosław |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196197/ https://www.ncbi.nlm.nih.gov/pubmed/34117327 http://dx.doi.org/10.1038/s41598-021-91812-0 |
Ejemplares similares
-
The NnaR orphan response regulator is essential for the utilization of nitrate and nitrite as sole nitrogen sources in mycobacteria
por: Antczak, Magdalena, et al.
Publicado: (2018) -
Dissecting the RecA-(In)dependent Response to Mitomycin C in Mycobacterium tuberculosis Using Transcriptional Profiling and Proteomics Analyses
por: Brzostek, Anna, et al.
Publicado: (2021) -
Functional Disassociation Between the Protein Domains of MSMEG_4305 of Mycolicibacterium smegmatis (Mycobacterium smegmatis) in vivo
por: Czubat, Bożena, et al.
Publicado: (2020) -
Cholesterol Oxidase Is Indispensable in the Pathogenesis of Mycobacterium tuberculosis
por: Klink, Magdalena, et al.
Publicado: (2013) -
The Orphan Response Regulator Rv3143 Modulates the Activity of the NADH Dehydrogenase Complex (Nuo) in Mycobacterium tuberculosis via Protein–Protein Interactions
por: Płocińska, Renata, et al.
Publicado: (2022)