Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis

BACKGROUND: An increasing number of studies evidences that amyotrophic lateral sclerosis (ALS) is characterized by extensive alterations in different cell types and in different regions besides the CNS. We previously reported the upregulation in ALS models of a gene called fibroblast-specific protei...

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Detalles Bibliográficos
Autores principales: Milani, Martina, Mammarella, Eleonora, Rossi, Simona, Miele, Chiara, Lattante, Serena, Sabatelli, Mario, Cozzolino, Mauro, D’Ambrosi, Nadia, Apolloni, Savina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196441/
https://www.ncbi.nlm.nih.gov/pubmed/34118929
http://dx.doi.org/10.1186/s12974-021-02184-1

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