Frequency detection of BRAF V600E mutation in a cohort of pediatric langerhans cell histiocytosis patients by next-generation sequencing

BACKGROUND: Langerhans cell histiocytosis (LCH) is a rare neoplastic disease that occurs in both children and adults, and BRAF V600E is detected in up to 64% of the patients. Several studies have discussed the associations between BRAF V600E mutation and clinicopathological manifestations, but no cl...

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Detalles Bibliográficos
Autores principales: Feng, Shunqiao, Han, Lin, Yue, Mei, Zhong, Dixiao, Cao, Jing, Guo, Yibing, Sun, Yanling, Zhang, Hao, Cao, Zhenhua, Cui, Xiaodai, Liu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196454/
https://www.ncbi.nlm.nih.gov/pubmed/34116682
http://dx.doi.org/10.1186/s13023-021-01912-3

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