Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog

BACKGROUND: Succinate dehydrogenase (Complex II) plays a dual role in respiration by catalyzing the oxidation of succinate to fumarate in the mitochondrial Krebs cycle and transferring electrons from succinate to ubiquinone in the mitochondrial electron transport chain (ETC). Mutations in Complex II...

Descripción completa

Detalles Bibliográficos
Autores principales: Bandara, Aloka B., Drake, Joshua C., Brown, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196461/
https://www.ncbi.nlm.nih.gov/pubmed/34118887
http://dx.doi.org/10.1186/s12860-021-00370-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196461/
https://www.ncbi.nlm.nih.gov/pubmed/34118887
http://dx.doi.org/10.1186/s12860-021-00370-w

Ejemplares similares