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Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulation

Bcl-x pre-mRNA splicing serves as a typical example to study the impact of alternative splicing in the modulation of cell death. Dysregulation of Bcl-x apoptotic isoforms caused by precarious equilibrium splicing is implicated in genesis and development of multiple human diseases, especially cancers...

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Detalles Bibliográficos
Autores principales:	Dou, Zhihui, Zhao, Dapeng, Chen, Xiaohua, Xu, Caipeng, Jin, Xiaodong, Zhang, Xuetian, Wang, Yupei, Xie, Xiaodong, Li, Qiang, Di, Cuixia, Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196531/ https://www.ncbi.nlm.nih.gov/pubmed/34118966 http://dx.doi.org/10.1186/s13046-021-02001-w

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