Cargando…

Omega-3 PUFAs Suppress IL-1β-Induced Hyperactivity of Immunoproteasomes in Astrocytes

The role of immunoproteasome (iP) in astroglia, the cellular component of innate immunity, has not been clarified. The results so far indicate that neuroinflammation, a prominent hallmark of Alzheimer’s disease, strongly activates the iP subunits expression. Since omega-3 PUFAs possess anti-inflamma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zgorzynska, Emilia, Dziedzic, Barbara, Markiewicz, Monika, Walczewska, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196670/ https://www.ncbi.nlm.nih.gov/pubmed/34063751 http://dx.doi.org/10.3390/ijms22115410

Ejemplares similares

Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation
por: Zgórzyńska, Emilia, et al.
Publicado: (2021)

Docosahexaenoic Acid (DHA) Inhibits FADS2 Expression in Astrocytes but Increases Survival of Neurons Co-cultured with DHA-enriched Astrocytes
por: Bewicz-Binkowska, Dorota, et al.
Publicado: (2019)

An Overview of the Nrf2/ARE Pathway and Its Role in Neurodegenerative Diseases
por: Zgorzynska, Emilia, et al.
Publicado: (2021)

Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs
por: Tribulova, Narcis, et al.
Publicado: (2017)

Efficacy of omega-3 PUFAs in depression: A meta-analysis
por: Liao, Yuhua, et al.
Publicado: (2019)

Omega-3 PUFA vs. NSAIDs for Preventing Cardiac Inflammation
por: Ye, Jiayu, et al.
Publicado: (2018)

The Role of Vitamin D and Omega-3 PUFAs in Islet Transplantation
por: Infante, Marco, et al.
Publicado: (2019)

Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions
por: Lands, Bill
Publicado: (2015)

Correction: Efficacy of omega-3 PUFAs in depression: A meta-analysis
por: Liao, Yuhua, et al.
Publicado: (2021)

Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis
por: Ciccone, Lidia, et al.
Publicado: (2023)

Overconsumption of Omega-6 Polyunsaturated Fatty Acids (PUFAs) versus Deficiency of Omega-3 PUFAs in Modern-Day Diets: The Disturbing Factor for Their “Balanced Antagonistic Metabolic Functions” in the Human Body
por: Mariamenatu, Abeba Haile, et al.
Publicado: (2021)

Immunoproteasome Activity in Chronic Lymphocytic Leukemia as a Target of the Immunoproteasome-Selective Inhibitors
por: Besse, Andrej, et al.
Publicado: (2022)

The impact of regional astrocyte interferon-γ signaling during chronic autoimmunity: a novel role for the immunoproteasome
por: Smith, Brandon C., et al.
Publicado: (2020)

Plasma omega-3 PUFA and white matter mediated executive decline in older adults
por: Bowman, Gene L., et al.
Publicado: (2013)

Comparative Analysis and Distribution of Omega-3 lcPUFA Biosynthesis Genes in Marine Molluscs
por: Surm, Joachim M., et al.
Publicado: (2015)

Omega-3 PUFA Responders and Non-Responders and the Prevention of Lipid Dysmetabolism and Related Diseases
por: Serini, Simona, et al.
Publicado: (2020)

Increased LC PUFA Levels in the Serum of Pregnant Women and Their Children as a Result of Dietary Supplementation with ‘Omega’ Fatty Acids
por: Broś-Konopielko, Magdalena, et al.
Publicado: (2023)

Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs
por: Brown, M D, et al.
Publicado: (2006)

Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells
por: Mobraten, Kaia, et al.
Publicado: (2013)

Regulation of Immunoproteasome Function in the Lung
por: Keller, Ilona E., et al.
Publicado: (2015)

Dysfunctional immunoproteasomes in autoinflammatory diseases
por: Arimochi, Hideki, et al.
Publicado: (2016)

On the Role of the Immunoproteasome in Protein Homeostasis
por: Basler, Michael, et al.
Publicado: (2021)

The Function of Immunoproteasomes—An Immunologists’ Perspective
por: van den Eshof, Bart L., et al.
Publicado: (2021)

Alteration of Bile Acids and Omega-6 PUFAs Are Correlated With the Progression and Prognosis of Drug-Induced Liver Injury
por: Zhao, Shuang, et al.
Publicado: (2022)

Supplementation with polyunsaturated fatty acids (PUFAs) in the management of attention deficit hyperactivity disorder (ADHD)
por: Banaschewski, Tobias, et al.
Publicado: (2018)

The Effects of Vitamin E and Omega-3 PUFAs on Endothelial Function among Adolescents with Metabolic Syndrome
por: Ahmadi, Alireza, et al.
Publicado: (2014)

Metabolic and Metabolomic Insights Regarding the Omega-3 PUFAs Intake in Type 1 Diabetes Mellitus
por: Purdel, Carmen, et al.
Publicado: (2021)

Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity
por: Benova, Andrea, et al.
Publicado: (2023)

Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome
por: Liu, Haiming M., et al.
Publicado: (2016)

Dietary Omega-6/Omega-3 Polyunsaturated Fatty Acid (PUFA) and Omega-3 Are Associated With General and Abdominal Obesity in Adults: UK National Diet and Nutritional Survey
por: Albar, Salwa A
Publicado: (2022)

Possible Role of CYP450 Generated Omega-3/Omega-6 PUFA Metabolites in the Modulation of Blood Pressure and Vascular Function in Obese Children
por: Bonafini, Sara, et al.
Publicado: (2018)

Effect of Dietary Fats on Oxidative-Antioxidative Status of Blood in Rats
por: Walczewska, Anna, et al.
Publicado: (2010)

Immunoproteasome Function in Normal and Malignant Hematopoiesis
por: Tubío-Santamaría, Nuria, et al.
Publicado: (2021)

Immunoproteasome inhibition attenuates experimental psoriasis
por: del Rio Oliva, Marta, et al.
Publicado: (2022)

PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis
por: Liu, Menghan, et al.
Publicado: (2014)

Omega-3 PUFA intake and the risk of digestive system cancers: A meta-analysis of observational studies
por: Wang, Jian, et al.
Publicado: (2020)

MON-129 Analysis of Omega3 PUFAs Status Among the Female and Male Population of the Moscow Region
por: Vorslov, Leonid, et al.
Publicado: (2020)

Suppression of prostate cancer and amelioration of the immunosuppressive tumor microenvironment through selective immunoproteasome inhibition
por: Koerner, Julia, et al.
Publicado: (2022)

Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake
por: Santoro, Nicola, et al.
Publicado: (2012)

Immunoproteasome Inhibition Ameliorates Aged Dystrophic Mouse Muscle Environment
por: Tripodi, Luana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6jt5s6iqhnh4uaf4ms30jlckto