Inflammation-Induced Tumorigenesis and Metastasis

Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and metastasis through various mechanisms and is now recognized as a hallmark of cancer and an attractive therapeutic target in cancer. In this review, we discuss recent advances in molecular mechanisms of how infla...

Descripción completa

Detalles Bibliográficos
Autores principales: Hibino, Sana, Kawazoe, Tetsuro, Kasahara, Hidenori, Itoh, Shinji, Ishimoto, Takatsugu, Sakata-Yanagimoto, Mamiko, Taniguchi, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196678/
https://www.ncbi.nlm.nih.gov/pubmed/34063828
http://dx.doi.org/10.3390/ijms22115421
Descripción
Sumario:Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and metastasis through various mechanisms and is now recognized as a hallmark of cancer and an attractive therapeutic target in cancer. In this review, we discuss recent advances in molecular mechanisms of how inflammation promotes tumorigenesis and metastasis and suppresses anti-tumor immunity in various types of solid tumors, including esophageal, gastric, colorectal, liver, and pancreatic cancer as well as hematopoietic malignancies.

Ejemplares similares