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Structural Perspectives on the Mechanism of Soluble Guanylate Cyclase Activation

The enzyme soluble guanylate cyclase (sGC) is the prototypical nitric oxide (NO) receptor in humans and other higher eukaryotes and is responsible for transducing the initial NO signal to the secondary messenger cyclic guanosine monophosphate (cGMP). Generation of cGMP in turn leads to diverse physi...

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Detalles Bibliográficos
Autores principales: Wittenborn, Elizabeth C., Marletta, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196705/
https://www.ncbi.nlm.nih.gov/pubmed/34064029
http://dx.doi.org/10.3390/ijms22115439

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