Cargando…
KRAS G12C Mutations in NSCLC: From Target to Resistance
SIMPLE SUMMARY: A better understanding of the role of KRAS and its different mutations has led to the development of specific small-molecule inhibitors able to target KRAS G12C, an oncogenic driver mutation in a number of cancers, including non-small cell lung cancer. While these therapies hold grea...
Autores principales: | Addeo, Alfredo, Banna, Giuseppe Luigi, Friedlaender, Alex |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196854/ https://www.ncbi.nlm.nih.gov/pubmed/34064232 http://dx.doi.org/10.3390/cancers13112541 |
Ejemplares similares
-
New emerging targets in cancer immunotherapy: the role of TIM3
por: Friedlaender, Alex, et al.
Publicado: (2019) -
The Landscape of Immunotherapy Resistance in NSCLC
por: Frisone, Daniele, et al.
Publicado: (2022) -
Drugging KRAS: current perspectives and state-of-art review
por: Parikh, Kaushal, et al.
Publicado: (2022) -
Stepping in the right direction but still some ways to go
por: Addeo, Alfredo, et al.
Publicado: (2019) -
Tarlatamab: a potential new option for recurrent small cell lung cancer
por: Addeo, Alfredo, et al.
Publicado: (2023)