CSF1/CSF1R Axis Blockade Limits Mesothelioma and Enhances Efficiency of Anti-PDL1 Immunotherapy

SIMPLE SUMMARY: CSF1/CSF1R signaling mediates tumor-associated macrophages recruitment and M2 polarization. M2 TAMs are dominant immune populations infiltrating mesothelioma tumors. We evaluated the role of CSF1/CSF1R axis blockade in tumor-infiltrating immune subsets. We also examined the effect of...

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Detalles Bibliográficos
Autores principales: Magkouta, Sophia Fotiou, Vaitsi, Photene Christou, Pappas, Apostolos Georgiou, Iliopoulou, Marianthi, Kosti, Chrysavgi Nikolaou, Psarra, Katherina, Kalomenidis, Ioannis Theodorou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196870/
https://www.ncbi.nlm.nih.gov/pubmed/34067348
http://dx.doi.org/10.3390/cancers13112546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196870/
https://www.ncbi.nlm.nih.gov/pubmed/34067348
http://dx.doi.org/10.3390/cancers13112546

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